Widdrol, a sesquiterpene isolated from Juniperus chinensis, inhibits angiogenesis by targeting vascular endothelial growth factor receptor 2 signaling

S Jin, HJ Yun, HY Jeong, YN Oh… - Oncology …, 2015 - spandidos-publications.com
Widdrol is an odorous compound derived from Juniperus chinensis that is widely used in
traditional medicine to treat fever, inflammation and cancer. It was previously reported that …

Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT …

KKL Chan, MKY Siu, Y Jiang, J Wang, THY Leung… - Cancer cell …, 2018 - Springer
Background Ovarian cancer is the most lethal gynaecological malignancy. Chemotherapy is
the main stay of treatment for metastatic disease, with modest response rates but significant …

Amentoflavone induces anti-angiogenic and anti-metastatic effects through suppression of NF-κB activation in MCF-7 cells

JH Chen, WL Chen, YC Liu - Anticancer Research, 2015 - ar.iiarjournals.org
The aim of the present study was to investigate whether amentoflavone induces anti-
angiogenic and anti-metastatic effects through suppression of NF-κB activation in breast …

Echinacoside inhibits the proliferation, migration, invasion and angiogenesis of ovarian cancer cells through PI3K/AKT pathway

J Liu, N Tang, N Liu, P Lei, F Wang - Journal of molecular histology, 2022 - Springer
Echinacoside is a group of natural compounds extracted from medicinal plants Cistanche
and Echinacea, which has neuroprotective, antiaging, immunomodulatory and anticancer …

Flavones inhibit breast cancer proliferation through the Akt/FOXO3a signaling pathway

CH Lin, CY Chang, KR Lee, HJ Lin, TH Chen, L Wan - BMC cancer, 2015 - Springer
Background Flavones found in plants display various biological activities, including anti-
allergic, anti-viral, anti-inflammatory, anti-oxidation, and anti-tumor effects. In this study, we …

EGCG, a major green tea catechin suppresses breast tumor angiogenesis and growth via inhibiting the activation of HIF-1α and NFκB, and VEGF expression

JW Gu, KL Makey, KB Tucker, E Chinchar, X Mao, I Pei… - Vascular cell, 2013 - Springer
The role of EGCG, a major green tea catechin in breast cancer therapy is poorly understood.
The present study tests the hypothesis that EGCG can inhibit the activation of HIF-1α and …

Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2–STAT3 signaling pathway

Y Dong, B Lu, X Zhang, J Zhang, L Lai, D Li… - …, 2010 - academic.oup.com
Cucurbitacin E (CuE, α-elaterin), a tetracyclic triterpenes compound from folk traditional
Chinese medicine plants, has been shown to inhibit cancer cell growth, inflammatory …

Delphinidin inhibits angiogenesis through the suppression of HIF-1α and VEGF expression in A549 lung cancer cells

MH Kim, YJ Jeong, HJ Cho, HS Hoe… - Oncology …, 2017 - spandidos-publications.com
Delphinidin, a polyphenol that belongs to the group of anthocyanidins and is abundant in
many pigmented fruits and vegetables, possesses important antioxidant, anti‑inflammatory …

trans- 3,4,5′-Trihydroxystibene Inhibits Hypoxia-Inducible Factor 1α and Vascular Endothelial Growth Factor Expression in Human Ovarian Cancer …

Z Cao, J Fang, C Xia, X Shi, BH Jiang - Clinical cancer research, 2004 - AACR
Abstract trans-3, 4, 5′-Trihydroxystibene (resveratrol) is a natural product commonly found
in the human diet and has been shown recently to have anticancer effects on various human …

[HTML][HTML] The flavonoid nobiletin inhibits tumor growth and angiogenesis of ovarian cancers via the Akt pathway

J Chen, AY Chen, H Huang, X Ye… - International …, 2015 - spandidos-publications.com
Despite its importance, the death rate of ovarian cancer has remained unchanged over the
past five decades, demanding an improvement in prevention and treatment of this …