[HTML][HTML] Anticancer effect of icaritin inhibits cell growth of colon cancer through reactive oxygen species, Bcl‑2 and cyclin D1/E signaling

C Li, W Peng, X Song, Q Wang… - Oncology …, 2016 - spandidos-publications.com
Icaritin has an advantage in enhancing immunity. Besides, with its anticancer effect, it may
be of great help in cancer treatment and recovery of cancer patients. As a result, icaritin is …

Decursin and decursinol angelate inhibit VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway

MH Jung, SH Lee, EM Ahn, YM Lee - Carcinogenesis, 2009 - academic.oup.com
Inhibition of angiogenesis is an attractive approach for the treatment of angiogenic diseases,
such as cancer. Vascular endothelial growth factor (VEGF) is one of the most important …

Acacetin inhibits the invasion and migration of human non-small cell lung cancer A549 cells by suppressing the p38α MAPK signaling pathway

ST Chien, SS Lin, CK Wang, YB Lee, KS Chen… - Molecular and cellular …, 2011 - Springer
Lung cancer is one of the most common malignancies in the world and its metastasis is the
major cause of death in cancer patients. Acacetin (5, 7-dihydroxy-4′-methoxyflavone), a …

Huaier aqueous extract inhibits ovarian cancer cell motility via the AKT/GSK3β/β-catenin pathway

X Yan, T Lyu, N Jia, Y Yu, K Hua, W Feng - PloS one, 2013 - journals.plos.org
Traditional Chinese medicine has gained popularity due to its ability to kill tumor cells.
Recently, the apoptotic and anti-angiogenic effects of Trametes robiniophila murr (Huaier) …

Evodiamine exerts anti-tumor effects against hepatocellular carcinoma through inhibiting β-catenin-mediated angiogenesis

L Shi, F Yang, F Luo, Y Liu, F Zhang, M Zou, Q Liu - Tumor Biology, 2016 - Springer
Hepatocellular carcinoma (HCC) is a highly vascular tumor with high microvessel density
and high levels of circulating vascular endothelial growth factor (VEGF). Thus, the …

Echinacoside regulates PI3K/AKT/HIF-1α/VEGF cross signaling axis in proliferation and apoptosis of breast cancer

H Liang, G Yin, G Shi, Z Liu, X Liu, J Li - Analytical Biochemistry, 2024 - Elsevier
Context Echinacoside (ECH) is a natural anti-cancer compound and is of great value in
cancer treatment. However, the mechanism underlying this effect on breast cancer (BC) was …

Targeted inhibition of tumor survival, metastasis and angiogenesis by Acacia ferruginea mediated regulation of VEGF, inflammatory mediators, cytokine profile and …

KM Sakthivel, C Guruvayoorappan - Regulatory Toxicology and …, 2018 - Elsevier
Acacia ferruginea extract (AFE) was studied for anti-metastasis/-angiogenesis activity
against B16F-10 melanoma cells in C57BL/6 mice. In vitro cytotoxicity of AFE was first …

Oleanolic acid inhibits colorectal cancer angiogenesis by blocking the VEGFR2 signaling pathway

G Niu, L Sun, Y Pei, D Wang - Anti-Cancer Agents in Medicinal …, 2018 - ingentaconnect.com
Background: Angiogenesis is a crucial process that regulated by multiple intracellular
signaling pathways including MEK/ERK and JNK/SAPK. Thus, many inhibitors have …

Amentoflavone inhibits hepatocellular carcinoma progression through blockage of ERK/NF-ĸB activation

KC Lee, WT Chen, YC Liu, SS Lin, FT Hsu - in vivo, 2018 - iv.iiarjournals.org
Aim: The aim of the present study was to confirm therapeutic efficacy and find probable
mechanism of action of amentoflavone in hepatocellular carcinoma (HCC) in vivo. Materials …

Quercetin attenuates metastatic ability of human metastatic ovarian cancer cells via modulating multiple signaling molecules involved in cell survival, proliferation …

T Dhanaraj, M Mohan, J Arunakaran - Archives of Biochemistry and …, 2021 - Elsevier
Ovarian cancer is the most deadly gynaecology related cancer due to its high metastasizing
ability. Quercetin is the most abundant flavonoids received increased interest due to its anti …