Oleanolic acid inhibits colorectal cancer angiogenesis by blocking the VEGFR2 signaling pathway

G Niu, L Sun, Y Pei, D Wang - Anti-Cancer Agents in Medicinal …, 2018 - ingentaconnect.com
Background: Angiogenesis is a crucial process that regulated by multiple intracellular
signaling pathways including MEK/ERK and JNK/SAPK. Thus, many inhibitors have …

Induction of growth cessation by acacetin via β-catenin pathway and apoptosis by apoptosis inducing factor activation in colorectal carcinoma cells

N Prasad, JR Sharma, UCS Yadav - Molecular biology reports, 2020 - Springer
Acacetin, a bioflavanoid, contains anti-inflammatory and anti-cancer activities as shown in
different experimental models. However, its anticancer potential and mechanism of action …

Quercetin attenuates metastatic ability of human metastatic ovarian cancer cells via modulating multiple signaling molecules involved in cell survival, proliferation …

T Dhanaraj, M Mohan, J Arunakaran - Archives of Biochemistry and …, 2021 - Elsevier
Ovarian cancer is the most deadly gynaecology related cancer due to its high metastasizing
ability. Quercetin is the most abundant flavonoids received increased interest due to its anti …

Amentoflavone inhibits hepatocellular carcinoma progression through blockage of ERK/NF-ĸB activation

KC Lee, WT Chen, YC Liu, SS Lin, FT Hsu - in vivo, 2018 - iv.iiarjournals.org
Aim: The aim of the present study was to confirm therapeutic efficacy and find probable
mechanism of action of amentoflavone in hepatocellular carcinoma (HCC) in vivo. Materials …

Herbal compound farnesiferol C exerts antiangiogenic and antitumor activity and targets multiple aspects of VEGFR1 (Flt1) or VEGFR2 (Flk1) signaling cascades

JH Lee, S Choi, Y Lee, HJ Lee, KH Kim, KS Ahn… - Molecular cancer …, 2010 - AACR
Farnesiferol C (FC) is one of the major compounds isolated from Ferula assafoetida, an
Asian herbal spice used for cancer treatment as a folk remedy. Here, we examined the …

Icariside II suppresses the tumorigenesis and development of ovarian cancer by regulating miR‐144‐3p/IGF2R axis

D Yuan, T Guo, H Qian, H Ge, Y Zhao… - Drug Development …, 2022 - Wiley Online Library
Ovarian cancer is one of the three major gynecological malignancies. It has been reported
that Icariside II was able to block the occurrence and development of ovarian cancer …

Gallic acid, a phenolic compound, exerts anti-angiogenic effects via the PTEN/AKT/HIF-1α/VEGF signaling pathway in ovarian cancer cells

Z He, AY Chen, Y Rojanasakul… - Oncology …, 2016 - spandidos-publications.com
Gallic acid (GA), a polyphenol, is widely found in numerous fruits and vegetables,
particularly in hickory nuts. In the present study, we found that gallic acid, a natural phenolic …

[PDF][PDF] Angiogenic pathway inhibition of Corydalis yanhusuo and berberine in human umbilical vein endothelial cells

JL Gao, JM Shi, SMY Lee, QW Zhang… - Oncology …, 2006 - researchgate.net
Corydalis yanhusuo, a well-known traditional Chinese medicine, is widely used in China as
an analgesic for patients with terminal cancer. In this study, we want to expose the …

CAPE suppresses VEGFR-2 activation, and tumor neovascularization and growth

TW Chung, SJ Kim, HJ Choi, CH Kwak… - Journal of molecular …, 2013 - Springer
The growth and metastasis of human solid tumors and the development of conditions such
as diabetic retinopathy, rheumatoid arthritis, inflammatory psoriasis, and others are …

Nobiletin Inhibits Angiogenesis by Regulating Src/FAK/STAT3-Mediated Signaling through PXN in ER+ Breast Cancer Cells

N Sp, DY Kang, YH Joung, JH Park, WS Kim… - International Journal of …, 2017 - mdpi.com
Tumor angiogenesis is one of the major hallmarks of tumor progression. Nobiletin is a
natural flavonoid isolated from citrus peel that has anti-angiogenic activity. Steroid receptor …