[HTML][HTML] A Role for LHC1 in Higher Order Structure and Complement Binding of the Cryptococcus neoformans Capsule

YD Park, S Shin, J Panepinto, J Ramos, J Qiu… - PLoS …, 2014 - journals.plos.org
Polysaccharide capsules are important virulence factors for many microbial pathogens
including the opportunistic fungus Cryptococcus neoformans. In the present study, we …

The capsule of the fungal pathogen Cryptococcus neoformans

O Zaragoza, ML Rodrigues, M De Jesus… - Advances in applied …, 2009 - Elsevier
The capsule of the fungal pathogen Cryptococcus neoformans has been studied extensively
in recent decades and a large body of information is now available to the scientific …

[HTML][HTML] Exploring Cryptococcus neoformans capsule structure and assembly with a hydroxylamine-armed fluorescent probe

CJ Crawford, RJB Cordero, L Guazzelli… - Journal of Biological …, 2020 - ASBMB
Chemical biology is an emerging field that enables the study and manipulation of biological
systems with probes whose reactivities provide structural insights. The opportunistic fungal …

Cryptococcus neoformans capsular polysaccharides form branched and complex filamentous networks viewed by high-resolution microscopy

GRS Araujo, GN Fontes, D Leão, GM Rocha… - Journal of structural …, 2016 - Elsevier
Cryptococcus neoformans is a fungal pathogen that causes life-threatening infections in
immunocompromised individuals. Its main virulence factor is an extracellular polysaccharide …

[HTML][HTML] Capsules from Pathogenic and Non-Pathogenic Cryptococcus spp. Manifest Significant Differences in Structure and Ability to Protect against Phagocytic …

GS Araujo, FL Fonseca, B Pontes, A Torres… - PloS one, 2012 - journals.plos.org
Capsule production is common among bacterial species, but relatively rare in eukaryotic
microorganisms. Members of the fungal Cryptococcus genus are known to produce …

Systematic capsule gene disruption reveals the central role of galactose metabolism on Cryptococcus neoformans virulence

F Moyrand, T Fontaine, G Janbon - Molecular microbiology, 2007 - Wiley Online Library
The polysaccharidic capsule is the main virulence factor of Cryptococcus neoformans. It
primarily comprised of two polysaccharides: glucuronoxylomannan (GXM, 88% of the …

The capsular dynamics of Cryptococcus neoformans

D McFadden, O Zaragoza, A Casadevall - TRENDS in Microbiology, 2006 - cell.com
Cryptococcus neoformans is a soil-dwelling fungus that causes life-threatening illness in
immunocompromised individuals and latently infects many healthy individuals. C …

[HTML][HTML] Cryptococcus neoformans capsule regrowth experiments reveal dynamics of enlargement and architecture

MP Wear, E Jacobs, S Wang, SA McConnell… - Journal of Biological …, 2022 - ASBMB
The polysaccharide capsule of fungal pathogen Cryptococcus neoformans is a critical
virulence factor that has historically evaded complete characterization. Cryptococcal …

How does Cryptococcus get its coat?

TL Doering - Trends in microbiology, 2000 - cell.com
During the past few decades, increasing attention has focused on pathogenic fungi both as
fascinating research subjects and as the agents of serious illness in diverse patient …

The capsule of Cryptococcus neoformans

A Casadevall, C Coelho, RJB Cordero, Q Dragotakes… - Virulence, 2019 - Taylor & Francis
The capsule of Cryptococcus neoformans is its dominant virulence factor and plays a key
role in the biology of this fungus. In this essay, we focus on the capsule as a cellular …