The capsule is certainly the most prominent virulence factor in Cryptococcus neoformans:
acapsular strains are avirulent, and capsular polysaccharides have a deleterious effect on …

Cryptococcus neoformans is a pathogenic fungus responsible for severe opportunistic
infections. The most prominent feature of this yeast is its elaborate polysaccharide capsule …

Several genes are essential for Cryptococcus neoformans capsule synthesis, but their
functions are unknown. We examined the localization of glucuronoxylomannan (GXM) in …

Abstract Complement component 3 (C3) is the major opsonin for the pathogenic fungus
Cryptococcus neoformans in the non‐immune host. However, the efficiency of complement …

The cryptococcal capsule is a critical virulence factor of an important pathogen, but little is
known about how it is associated with the cell or released into the environment. Two mutants …

The human pathogenic fungus Cryptococcus neoformans has a large polysaccharide (PS)
capsule and releases copious amounts of PS into cultures and infected tissues. The …

Cryptococcus neoformans, which causes fatal infection in immunocompromised individuals,
has an elaborate polysaccharide capsule surrounding its cell wall. The cryptococcal capsule …

ABSTRACT Molecules composed of β-1, 4-linked N-acetylglucosamine (GlcNAc) and
deacetylated glucosamine units play key roles as surface constituents of the human …

Cryptococcus neoformans is an opportunistic human pathogen that causes life‐threatening
meningitis. In this fungus, the cell wall is exceptionally not the outermost structure due to the …

The capsular components of the human pathogen Cryptococcus neoformans are
transported to the extracellular space and then used for capsule enlargement by distal …