Introduction to epigenomics and epigenome-wide analysis

MJ Fazzari, JM Greally - Statistical Methods in Molecular Biology, 2010 - Springer
Epigenetics is the study of heritable change other than those encoded in DNA sequence.
Cytosine methylation of DNA at CpG dinucleotides is the most well-studied epigenetic …

Profiling DNA methylomes from microarray to genome-scale sequencing

YW Huang, THM Huang… - Technology in cancer …, 2010 - journals.sagepub.com
DNA cytosine methylation is a central epigenetic modification which plays critical roles in
cellular processes including genome regulation, development and disease. Here, we review …

Principles and challenges of genome-wide DNA methylation analysis

PW Laird - Nature Reviews Genetics, 2010 - nature.com
Methylation of cytosine bases in DNA provides a layer of epigenetic control in many
eukaryotes that has important implications for normal biology and disease. Therefore …

Profiling genome-wide DNA methylation

WS Yong, FM Hsu, PY Chen - Epigenetics & chromatin, 2016 - Springer
DNA methylation is an epigenetic modification that plays an important role in regulating
gene expression and therefore a broad range of biological processes and diseases. DNA …

Genome-scale DNA methylation analysis

SD Fouse, RP Nagarajan, JF Costello - Epigenomics, 2010 - Taylor & Francis
The haploid human genome contains approximately 29 million CpGs that exist in a
methylated, hydroxymethylated or unmethylated state, collectively referred to as the DNA …

Deciphering the epigenetic code: an overview of DNA methylation analysis methods

M Umer, Z Herceg - Antioxidants & redox signaling, 2013 - liebertpub.com
Significance: Methylation of cytosine in DNA is linked with gene regulation, and this has
profound implications in development, normal biology, and disease conditions in many …

Genome‐wide DNA methylation profiling

M Bibikova, JB Fan - Wiley Interdisciplinary Reviews: Systems …, 2010 - Wiley Online Library
DNA methylation plays a critical role in the regulation of gene expression. The ability to
access the methylation status for a large number of genes or the entire genome should …

DNA methylation methods: Global DNA methylation and methylomic analyses

S Li, TO Tollefsbol - Methods, 2021 - Elsevier
DNA methylation provides a pivotal layer of epigenetic regulation in eukaryotes that has
significant involvement for numerous biological processes in health and disease. The …

Genome-wide analysis of DNA methylation patterns

D Zilberman, S Henikoff - 2007 - journals.biologists.com
Cytosine methylation is the most common covalent modification of DNA in eukaryotes. DNA
methylation has an important role in many aspects of biology, including development and …

Quantitative region-specific DNA methylation analysis by the EpiTYPER™ Technology

S Kunze - DNA Methylation Protocols, 2018 - Springer
DNA methylation plays a profound role in development and health as well as development
and progression of disease. High-throughput quantitative DNA methylation analysis is …