Role of hemodynamics in initiation/growth of intracranial aneurysms

MR Diagbouga, S Morel, P Bijlenga… - European journal of …, 2018 - Wiley Online Library
Background Intracranial aneurysm (IA) is a disease of the vascular wall resulting in
abnormal enlargement of the vessel lumen. It is a common pathology with a prevalence of …

Association of hemodynamic factors with intracranial aneurysm formation and rupture: systematic review and meta-analysis

A Can, R Du - Neurosurgery, 2016 - journals.lww.com
BACKGROUND: Recent evidence suggests a link between the magnitude and distribution of
hemodynamic factors and the formation and rupture of intracranial aneurysms. However …

Basic principles of hemodynamics and cerebral aneurysms

PM Munarriz, PA Gómez, I Paredes… - World neurosurgery, 2016 - Elsevier
Background Rupture is the most serious consequence of cerebral aneurysms, and its
likelihood depends on nonmodifiable and modifiable risk factors. Recent efforts have …

Wall shear stress gradient is independently associated with middle cerebral artery aneurysm development: a case-control CFD patient-specific study based on 77 …

M Zimny, E Kawlewska, A Hebda, W Wolański… - BMC neurology, 2021 - Springer
Background Previously published computational fluid dynamics (CFD) studies regarding
intracranial aneurysm (IA) formation present conflicting results. Our study analysed the …

Association between hemodynamics, morphology, and rupture risk of intracranial aneurysms: a computational fluid modeling study

T Qiu, G Jin, H Xing, H Lu - Neurological Sciences, 2017 - Springer
The objective of the study was to examine the correlations between intracranial aneurysm
morphology and wall shear stress (WSS) to identify reliable predictors of rupture risk …

The biophysical role of hemodynamics in the pathogenesis of cerebral aneurysm formation and rupture

S Soldozy, P Norat, M Elsarrag, A Chatrath… - Neurosurgical …, 2019 - thejns.org
The pathogenesis of intracranial aneurysms remains complex and multifactorial. While
vascular, genetic, and epidemiological factors play a role, nascent aneurysm formation is …

Magnitude and role of wall shear stress on cerebral aneurysm: computational fluid dynamic study of 20 middle cerebral artery aneurysms

M Shojima, M Oshima, K Takagi, R Torii, M Hayakawa… - Stroke, 2004 - Am Heart Assoc
Background and Purpose—Wall shear stress (WSS) is one of the main pathogenic factors in
the development of saccular cerebral aneurysms. The magnitude and distribution of the …

Wall shear stress at the initiation site of cerebral aneurysms

AJ Geers, HG Morales, I Larrabide, C Butakoff… - … and modeling in …, 2017 - Springer
Hemodynamics are believed to play an important role in the initiation of cerebral aneurysms.
In particular, studies have focused on wall shear stress (WSS), which is a key regulator of …

Association of wall shear stress with intracranial aneurysm rupture: systematic review and meta-analysis

G Zhou, Y Zhu, Y Yin, M Su, M Li - Scientific reports, 2017 - nature.com
To evaluate the relationship between wall shear stress (WSS) magnitude and cerebral
aneurysm rupture and provide new insight into the disparate computational fluid dynamics …

High WSS or low WSS? Complex interactions of hemodynamics with intracranial aneurysm initiation, growth, and rupture: toward a unifying hypothesis

H Meng, VM Tutino, J Xiang… - American Journal of …, 2014 - Am Soc Neuroradiology
Increasing detection of unruptured intracranial aneurysms, catastrophic outcomes from
subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective …