Differential epigenome-wide DNA methylation patterns in childhood obesity-associated asthma
While DNA methylation plays a role in T-helper (Th) cell maturation, its potential
dysregulation in the non-atopic Th1-polarized systemic inflammation observed in obesity …
dysregulation in the non-atopic Th1-polarized systemic inflammation observed in obesity …
Global hypomethylation in childhood asthma identified by genome‐wide DNA‐methylation sequencing preferentially affects enhancer regions
Background Childhood asthma is a result of a complex interaction of genetic and
environmental components causing epigenetic and immune dysregulation, airway …
environmental components causing epigenetic and immune dysregulation, airway …
Epigenome-wide association study of DNA methylation and adult asthma in the Agricultural Lung Health Study
Epigenome-wide studies of methylation in children support a role for epigenetic
mechanisms in asthma; however, studies in adults are rare and few have examined non …
mechanisms in asthma; however, studies in adults are rare and few have examined non …
Characteristic DNA methylation profiles in peripheral blood monocytes are associated with inflammatory phenotypes of asthma
LP Gunawardhana, PG Gibson, JL Simpson… - Epigenetics, 2014 - Taylor & Francis
Epigenetic changes including DNA methylation caused by environmental exposures may
contribute to the heterogeneous inflammatory response in asthma. Here we investigate …
contribute to the heterogeneous inflammatory response in asthma. Here we investigate …
Nasal DNA methylation differentiates severe from non‐severe asthma in African‐American children
Background Asthma is highly heterogeneous, and severity evaluation is key to asthma
management. DNA methylation (DNAm) contributes to asthma pathogenesis. This study …
management. DNA methylation (DNAm) contributes to asthma pathogenesis. This study …
DNA methylation and childhood asthma in the inner city
IV Yang, BS Pedersen, A Liu, GT O'Connor… - Journal of Allergy and …, 2015 - Elsevier
Background Epigenetic marks are heritable, influenced by the environment, direct the
maturation of T lymphocytes, and in mice enhance the development of allergic airway …
maturation of T lymphocytes, and in mice enhance the development of allergic airway …
Expression quantitative trait methylation analysis reveals methylomic associations with gene expression in childhood asthma
Background Nasal (airway) epithelial methylation profiles have been associated with
asthma, but the effects of such profiles on expression of distant cis-genes are largely …
asthma, but the effects of such profiles on expression of distant cis-genes are largely …
[HTML][HTML] Epigenome-wide meta-analysis of DNA methylation and childhood asthma
Background Epigenetic mechanisms, including methylation, can contribute to childhood
asthma. Identifying DNA methylation profiles in asthmatic patients can inform disease …
asthma. Identifying DNA methylation profiles in asthmatic patients can inform disease …
DNA methylation in childhood asthma: an epigenome-wide meta-analysis
CJ Xu, C Söderhäll, M Bustamante, N Baïz… - The lancet Respiratory …, 2018 - thelancet.com
Background DNA methylation profiles associated with childhood asthma might provide
novel insights into disease pathogenesis. We did an epigenome-wide association study to …
novel insights into disease pathogenesis. We did an epigenome-wide association study to …
DNA methylation in nasal epithelium, atopy, and atopic asthma in children: a genome-wide study
Background Epigenetic mechanisms could alter the airway epithelial barrier and ultimately
lead to atopic diseases such as asthma. We aimed to identify DNA methylation profiles that …
lead to atopic diseases such as asthma. We aimed to identify DNA methylation profiles that …
相关搜索
- dna methylation childhood asthma
- dna methylation meta analysis
- dna methylation atopic asthma
- dna methylation severe asthma
- dna methylation in nasal epithelium
- association study of dna methylation
- dna methylation profiles
- dna methylation inner city
- dna methylation sequencing
- global hypomethylation methylation sequencing
- enhancer regions methylation sequencing
- meta analysis childhood asthma
- methylation sequencing childhood asthma
- gene expression childhood asthma
- global hypomethylation childhood asthma
- enhancer regions childhood asthma