[PDF] academia.edu

TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic …

K Iljin, M Wolf, H Edgren, S Gupta, S Kilpinen… - Cancer research, 2006 - AACR
Translocations fusing the strong androgen-responsive gene, TMPRSS2, with ERG or other
oncogenic ETS factors may facilitate prostate cancer development. Here, we studied 18 …
被引用次数：309 相关文章 所有 13 个版本
[HTML] sciencedirect.com

[HTML][HTML] Comprehensive assessment of TMPRSS2 and ETS family gene aberrations in clinically localized prostate cancer

R Mehra, SA Tomlins, R Shen, O Nadeem, L Wang… - Modern Pathology, 2007 - Elsevier
Novel recurrent gene fusions between the androgen-regulated gene TMPRSS2 and the ETS
family members ERG, ETV1, or ETV4 have been recently identified as a common molecular …
被引用次数：377 相关文章 所有 16 个版本
[HTML] nih.gov

Characterization of TMPRSS2-ETS Gene Aberrations in Androgen-Independent Metastatic Prostate Cancer

R Mehra, SA Tomlins, J Yu, X Cao, L Wang, A Menon… - Cancer research, 2008 - AACR
Recurrent gene fusions between the androgen-regulated gene TMPRSS2 and the ETS
transcription factor family members ERG, ETV1, and ETV4 have been identified as a critical …
被引用次数：333 相关文章 所有 14 个版本
[PDF] academia.edu

Heterogeneity of TMPRSS2 Gene Rearrangements in Multifocal Prostate Adenocarcinoma: Molecular Evidence for an Independent Group of Diseases

R Mehra, B Han, SA Tomlins, L Wang, A Menon… - Cancer research, 2007 - AACR
Recurrent gene fusions between the androgen-regulated gene TMPRSS2 and the ETS
family transcription factors ERG, ETV1, and ETV4 have been identified in the majority of …
被引用次数：255 相关文章 所有 9 个版本
[PDF] eur.nl

TMPRSS2:ERG Fusion by Translocation or Interstitial Deletion Is Highly Relevant in Androgen-Dependent Prostate Cancer, But Is Bypassed in Late-Stage Androgen …

KG Hermans, R Van Marion, H Van Dekken, G Jenster… - Cancer research, 2006 - AACR
Recently, a unique fusion between the prostate-specific, androgen-regulated TMPRSS2
gene and the ETS genes ERG, ETV1, or ETV4 has been described in clinical prostate …
被引用次数：292 相关文章 所有 14 个版本
[PDF] academia.edu

TMPRSS2:ERG Fusion-Associated Deletions Provide Insight into the Heterogeneity of Prostate Cancer

S Perner, F Demichelis, R Beroukhim, FH Schmidt… - Cancer research, 2006 - AACR
Prostate cancer is a common and clinically heterogeneous disease with marked variability in
progression. The recent identification of gene fusions of the 5′-untranslated region of …
被引用次数：675 相关文章 所有 18 个版本
[PDF] sciencedirect.com

Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model

KD Mertz, SR Setlur, SM Dhanasekaran, F Demichelis… - Neoplasia, 2007 - Elsevier
Recent studies have established that a significant fraction of prostate cancers harbor a
signature gene fusion between the 5'region of androgen-regulated TMPRSS2 and an ETS …
被引用次数：170 相关文章 所有 17 个版本
[HTML] nih.gov

TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation

C Sun, A Dobi, A Mohamed, H Li, RL Thangapazham… - Oncogene, 2008 - nature.com
The high prevalence of TMPRSS2-ERG rearrangements (∼ 60%) in prostate cancer (CaP)
leads to androgenic induction of the ETS-related gene (ERG) expression. However, the …
被引用次数：328 相关文章 所有 15 个版本
[HTML] sciencedirect.com

[HTML][HTML] Prevalence of TMPRSS2–ERG and SLC45A3–ERG gene fusions in a large prostatectomy cohort

R Esgueva, S Perner, CJ LaFargue, V Scheble… - Modern Pathology, 2010 - Elsevier
The majority of prostate cancers harbor recurrent gene fusions between the hormone-
regulated TMPRSS2 and members of the ETS family of transcription factors, most commonly …
被引用次数：201 相关文章 所有 15 个版本
[HTML] nih.gov

TMPRSS2-ERG Gene Fusion Is Not Associated with Outcome in Patients Treated by Prostatectomy

A Gopalan, MA Leversha, JM Satagopan, Q Zhou… - Cancer research, 2009 - AACR
A significant number of prostate cancers have been shown to have recurrent chromosomal
rearrangements resulting in the fusion of the androgen-regulated TMPRSS2 promoter to a …
被引用次数：333 相关文章 所有 11 个版本