Background: Periostin is responsible for tissue regeneration, fibrosis, and wound healing via
its interaction with integrin. Recently, the role of periostin has been shown to contribute to …

Increased renal expression of periostin, a protein normally involved in embryonic and dental
development, correlates with the decline of renal function in experimental models and …

Periostin plays a crucial role in fibrosis, and acute kidney injury results in a high risk of
progression to chronic kidney disease. Therefore, we hypothesized that periostin was …

The continuous accumulation of extracellular matrix will eventually lead to glomerular
sclerosis, interstitial fibrosis, tubular atrophy and vascular sclerosis, which are involved in …

Periostin is a matricellular protein that is expressed in several tissues during embryonic
development; however, its expression in adults is mostly restricted to collagen-rich …

Background Periostin acts as an adhesion molecule during bone formation. Knowledge of
its expression in kidney injury is scant. Methods We investigated periostin function and …

Background The matricellular protein periostin has been associated with CKD progression
in animal models and human biopsy specimens. Periostin functions by interacting with …

To simulate clinical features in human chronic kidney disease (CKD), SD rats were
subjected to 5/6 nephrectomy in this study. We found that periostin gene was upregulated in …

Chronic kidney disease is an incurable to date pathology, with renal replacement therapy
through dialysis or transplantation being the only available option for end-stage patients. A …

Matricellular proteins participate in the pathogenesis of chronic kidney diseases. We
analyzed glomerular gene expression profiles from patients with proteinuric diseases to …