A novel gene prognostic signature based on differential DNA methylation in breast cancer

C Zhu, S Zhang, D Liu, Q Wang, N Yang… - Frontiers in …, 2021 - frontiersin.org
Background: DNA methylation played essential roles in regulating gene expression. The
impact of DNA methylation status on the occurrence and development of cancers has been …

Genome-wide analysis of methylation-driven genes and identification of an eight-gene panel for prognosis prediction in breast cancer

Y Kuang, Y Wang, W Zhai, X Wang, B Zhang… - Frontiers in …, 2020 - frontiersin.org
Background Aberrant DNA methylation is a crucial epigenetic regulator that is closely
related to the occurrence and development of various cancers, including breast cancer (BC) …

A seven‐DNA methylation signature as a novel prognostic biomarker in breast cancer

C Tao, R Luo, J Song, W Zhang… - Journal of Cellular …, 2020 - Wiley Online Library
Background Breast cancer (BC) is a common malignant tumor and its incidence and
mortality rates are ranked first among female cancers. So far, there has been no effective …

Integrative analysis of DNA methylation and gene expression to determine specific diagnostic biomarkers and prognostic biomarkers of breast cancer

M Zhang, Y Wang, Y Wang, L Jiang, X Li… - Frontiers in Cell and …, 2020 - frontiersin.org
Background: DNA methylation is a common event in the early development of various
tumors, including breast cancer (BRCA), which has been studies as potential tumor …

Prognostic biomarker identification and tumor classification in breast cancer patients by methylation and transcriptome analysis

X Zhong, G Zhong - FEBS Open Bio, 2021 - Wiley Online Library
Breast cancer is one of the most common and heterogeneous malignancies. Although the
prognosis of breast cancer has improved with the development of early screening, the …

Roadmap of DNA methylation in breast cancer identifies novel prognostic biomarkers

BP de Almeida, JD Apolónio, A Binnie… - BMC cancer, 2019 - Springer
Background Breast cancer is a highly heterogeneous disease resulting in diverse clinical
behaviours and therapeutic responses. DNA methylation is a major epigenetic alteration that …

Identification of differentially methylated genes as diagnostic and prognostic biomarkers of breast cancer

X Mao, Q Ye, G Zhang, J Jiang, H Zhao, Y Shao… - World journal of surgical …, 2021 - Springer
Background Aberrant DNA methylation is significantly associated with breast cancer.
Methods In this study, we aimed to determine novel methylation biomarkers using a …

DNA methylation patterns can estimate nonequivalent outcomes of breast cancer with the same receptor subtypes

M Zhang, S Zhang, Y Wen, Y Wang, Y Wei, H Liu… - PLoS …, 2015 - journals.plos.org
Breast cancer has various molecular subtypes and displays high heterogeneity. Aberrant
DNA methylation is involved in tumor origin, development and progression. Moreover …

A DNA methylation-based panel for the prognosis and diagnosis of patients with breast cancer and its mechanisms

XP Liu, J Hou, C Chen, L Guan, HK Hu… - Frontiers in molecular …, 2020 - frontiersin.org
Objective To identify DNA methylation related biomarkers in patients with breast cancer
(BC). Materials and Methods A total of seven BC methylation studies including 1,438 BC …

Aberrant DNA methylation impacts gene expression and prognosis in breast cancer subtypes

B Győrffy, G Bottai, T Fleischer… - … journal of cancer, 2016 - Wiley Online Library
DNA methylation has a substantial impact on gene expression, affecting the prognosis of
breast cancer (BC) patients dependent on molecular subtypes. In this study, we investigated …