Purpose: To characterize the pharmacokinetics and pharmacodynamics of oxaliplatin in
cancer patients with impaired renal function. Experimental Design: Thirty-four patients were …

Purpose: This study was undertaken to determine the toxicities, pharmacokinetics, and
maximum tolerated doses of oxaliplatin in patients with renal impairment and to develop …

Purpose: The pharmacokinetics (PK) of platinum was investigated and compared in patients
with normal (NRF) and impaired renal function (IRF), after they had received oxaliplatin at …

Oxaliplatin is an approved agent with clinical activity in the treatment of advanced colorectal
cancer. Preliminary pharmacokinetic evidence suggests that oxaliplatin is predominantly …

The objective of this study was to explore correlations between a variety of covariates and
oxaliplatin ultrafilterable and blood pharmacokinetic parameters. Data from 40 patients …

Abstract Oxaliplatin (cis-[(1 R, 2 R)-1, 2-cyclohexanediamine-N, N′] oxalato (2-)-O, O′]
platinum; Eloxatine) is a novel platinum coordination complex used for the treatment of …

Background Although cisplatin pharmacokinetics is well documented in patients with various
degrees of renal dysfunction, no information is available concerning cisplatin administration …

Oxaliplatin is a novel platinum complex used for the treatment of metastatic colorectal
carcinoma. The pharmacokinetics of the free fraction of oxaliplatin in blood were evaluated …

Pharmacokinetics of carboplatin were determined in a patient suffering from advanced
ovarian cancer with total hemodialysis-dependent chronic renal failure undergoing 3 …

Pharmacokinetics of Oxaliplatin in a Hemodialyzed Patient: Chemotherapy Dose
Adjustment and Timing of Dialysis - ScienceDirect Skip to main contentSkip to article …