Establishing, maintaining and modifying DNA methylation patterns in plants and animals

JA Law, SE Jacobsen - Nature Reviews Genetics, 2010 - nature.com
Cytosine DNA methylation is a stable epigenetic mark that is crucial for diverse biological
processes, including gene and transposon silencing, imprinting and X chromosome …

[引用][C] The flip side of DNA methylation

GL Verdine - Cell, 1994 - Elsevier
DNA methylation has come of age. For more than 40 years, it has been known that
eukaryotes tag their DNA by the covalent addition of a methyl group to cytosine residues; …

Eukaryotic DNA methylation and gene expression

A Weissbach, C Ward, A Bolden - Current topics in cellular regulation, 1989 - Elsevier
Publisher Summary This chapter discusses eukaryotic DNA methylation and gene
expression. The methylation of DNA in animal cells is a postreplicative process involving the …

Epigenetic mechanisms in mammals

JK Kim, M Samaranayake, S Pradhan - Cellular and molecular life …, 2009 - Springer
DNA and histone methylation are linked and subjected to mitotic inheritance in mammals.
Yet how methylation is propagated and maintained between successive cell divisions is not …

A Drosophila MBD family member is a transcriptional corepressor associated with specific genes

E Ballestar, LA Pile, DA Wassarman… - European Journal of …, 2001 - Wiley Online Library
DNA methylation in Drosophila melanogaster is restricted temporally during development
and occurs at a significantly lower frequency than in mammals. Thus, the regulatory …

New insights into mechanisms that regulate DNA methylation patterning

G Ficz - Journal of Experimental Biology, 2015 - journals.biologists.com
From a fertilised egg to a mature organism, cells divide and accumulate epigenetic
information, which is faithfully passed on to daughter cells. DNA methylation consolidates …

Plant DNA methyltransferases

EJ Finnegan, KA Kovac - Plant gene silencing, 2000 - Springer
DNA methylation is an important modification of DNA that plays a role in genome
management and in regulating gene expression during development. Methylation is carried …

DNA methylation and human disease

KD Robertson - Nature Reviews Genetics, 2005 - nature.com
DNA methylation is a crucial epigenetic modification of the genome that is involved in
regulating many cellular processes. These include embryonic development, transcription …

The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells

H Li, T Rauch, ZX Chen, PE Szabó, AD Riggs… - Journal of Biological …, 2006 - ASBMB
DNA CpG methylation can cooperate with histone H3 lysine 9 (H3-K9) methylation in
heterochromatin formation and gene silencing. Trimethylation of H3-K9 by the recently …

[HTML][HTML] DNA methylation systems and targets in plants

P Meyer - FEBS letters, 2011 - Elsevier
Plants contain three distinct DNA methyltransferase types that are responsible for the
establishment and maintenance of cytosine methylation patterns at heterochromatic and …