Human plasma-like medium (HPLM) induces Cryptococcus neoformans in vivo cell morphologies
E G. Mozo, O Ross, R Yuecel, IM Dambuza… - Msphere, 2024 - Am Soc Microbiol
The fungal pathogen Cryptococcus neoformans (C. neoformans) forms yeast cells of
different sizes and morphological characteristics during infection. These features are usually …
different sizes and morphological characteristics during infection. These features are usually …
The Intracellular Life of Cryptococcus neoformans
Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …
studies of human populations show a high prevalence of human infection, which rarely …
[HTML][HTML] The origin and maintenance of virulence for the human pathogenic fungus Cryptococcus neoformans
JN Steenbergen, A Casadevall - Microbes and infection, 2003 - Elsevier
The origin of virulence in environmental fungi that have no requirement for animal hosts in
their life cycle is enigmatic. Cryptococcus neoformans is a human pathogenic fungus with …
their life cycle is enigmatic. Cryptococcus neoformans is a human pathogenic fungus with …
Gene expression of diverse Cryptococcus isolates during infection of the human central nervous system
CH Yu, P Sephton-Clark, JL Tenor, DL Toffaletti… - Mbio, 2021 - Am Soc Microbiol
Cryptococcus neoformans is a major human central nervous system (CNS) fungal pathogen
causing considerable morbidity and mortality. In this study, we provide the widest view to …
causing considerable morbidity and mortality. In this study, we provide the widest view to …
[HTML][HTML] Cryptococcus and Phagocytes: Complex Interactions that Influence Disease Outcome
Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening
disease. These fungi commonly enter their host via inhalation into the lungs where they …
disease. These fungi commonly enter their host via inhalation into the lungs where they …
Virulence mechanisms and Cryptococcus neoformans pathogenesis
JA Alspaugh - Fungal Genetics and Biology, 2015 - Elsevier
The human fungal pathogen Cryptococcus neoformans is able to rapidly and effectively
adapt to varying conditions, favoring its survival in the environment and in the infected host …
adapt to varying conditions, favoring its survival in the environment and in the infected host …
Extracellular proteins of Cryptococcus neoformans and host antibody response
LC Chen, L Pirofski, A Casadevall - Infection and immunity, 1997 - Am Soc Microbiol
Proteins secreted by the fungal pathogen Cryptococcus neoformans may be involved in
invasion and could be useful in vaccine design. Despite the medical importance of this …
invasion and could be useful in vaccine design. Despite the medical importance of this …
Cryptococcus gattii isolates from the British Columbia cryptococcosis outbreak induce less protective inflammation in a murine model of infection than Cryptococcus …
PY Cheng, A Sham, JW Kronstad - Infection and immunity, 2009 - Am Soc Microbiol
The fungal pathogen Cryptococcus neoformans causes approximately one million cases of
cryptococcosis per year in people with AIDS. In contrast, the related species C. gattii is …
cryptococcosis per year in people with AIDS. In contrast, the related species C. gattii is …
Cryptococcus strains with different pathogenic potentials have diverse protein secretomes
LT Campbell, AR Simonin, C Chen, J Ferdous… - Eukaryotic …, 2015 - Am Soc Microbiol
Secreted proteins are the frontline between the host and pathogen. In mammalian hosts,
secreted proteins enable invasive infection and can modulate the host immune response …
secreted proteins enable invasive infection and can modulate the host immune response …
[PDF][PDF] Beyond the big three: systematic analysis of virulence factors in Cryptococcus neoformans
J Kronstad, WH Jung, G Hu - Cell Host & Microbe, 2008 - cell.com
The fungal pathogen Cryptococcus neoformans has three major virulence factors: growth at
37° C, capsule synthesis, and melanin formation. Recently in Cell, Liu et al.(2008) employed …
37° C, capsule synthesis, and melanin formation. Recently in Cell, Liu et al.(2008) employed …