[HTML][HTML] The Dynamics of Cryptococcus neoformans Cell and Transcriptional Remodeling during Infection

GJC Freitas, L Gouveia-Eufrasio, ECP Emidio… - Cells, 2022 - mdpi.com
The phenotypic plasticity of Cryptococcus neoformans is widely studied and demonstrated in
vitro, but its influence on pathogenicity remains unclear. In this study, we investigated the …

Cryptococcus neoformans Gene Expression during Experimental Cryptococcal Meningitis

BR Steen, S Zuyderduyn, DL Toffaletti, M Marra… - Eukaryotic …, 2003 - Am Soc Microbiol
Cryptococcus neoformans, an encapsulated basidiomycete fungus of medical importance, is
capable of crossing the blood-brain barrier and causing meningitis in both …

Complementation of a Capsule Deficient Cryptococcus neoformans with Cap64 Restores Virulence in a Murine Lung Infection

JA Wilder, GK Olson, YC Chang… - American journal of …, 2002 - atsjournals.org
Cryptococcosis is a systemic infection in humans caused by the opportunistic fungal
pathogen, Cryptococcus neoformans. The infection usually presents as chronic …

[HTML][HTML] Characterization of the virulence of Cryptococcus neoformans strains in an insect model

T Bouklas, E Diago-Navarro, X Wang, M Fenster… - Virulence, 2015 - Taylor & Francis
Cryptococcus neoformans is a fungal pathogen that causes disease in
immunocompromised individuals, especially in HIVC/AIDS patients, and organ transplant …

[HTML][HTML] Genome-Wide Transcription Study of Cryptococcus neoformans H99 Clinical Strain versus Environmental Strains

E Movahed, K Munusamy, GMY Tan, CY Looi, ST Tay… - PLoS …, 2015 - journals.plos.org
The infection of Cryptococcus neoformans is acquired through the inhalation of desiccated
yeast cells and basidiospores originated from the environment, particularly from bird's …

Adaptation of Cryptococcus neoformans to mammalian hosts: integrated regulation of metabolism and virulence

J Kronstad, S Saikia, ED Nielson, M Kretschmer… - Eukaryotic …, 2012 - Am Soc Microbiol
The basidiomycete fungus Cryptococcus neoformans infects humans via inhalation of
desiccated yeast cells or spores from the environment. In the absence of effective immune …

A Unique Chromosomal Rearrangement in the Cryptococcus neoformans var. grubii Type Strain Enhances Key Phenotypes Associated with Virulence

CA Morrow, IR Lee, EWL Chow, KL Ormerod… - MBio, 2012 - Am Soc Microbiol
The accumulation of genomic structural variation between closely related populations over
time can lead to reproductive isolation and speciation. The fungal pathogen Cryptococcus is …

Differential In Vitro Cytokine Induction by the Species of Cryptococcus gattii Complex

PF Herkert, JC Dos Santos, F Hagen… - Infection and …, 2018 - Am Soc Microbiol
Cryptococcal species vary in capsule and cell size, thermotolerance, geographic
distribution, and affected populations. Cryptococcus gattii sensu stricto and C. deuterogattii …

Molecular Typing of the Cryptococcus neoformans/Cryptococcus gattii Species Complex

W Meyer, F Gilgado, P Ngamskulrungroj… - … human pathogen to …, 2010 - Wiley Online Library
A large number of molecular typing techniques have been applied over the years to
discriminate between individual isolates that had been indistinguishable using conventional …

Mechanism of Cryptococcus meningoencephalitis

A Miyazato - Medical mycology journal, 2016 - europepmc.org
Cryptococcus neoformans and Cryptococcus gattii are fungal pathogens that cause
diseases in humans. Cryptococcal species mainly enter the body by inhalation and in most …