[HTML][HTML] DNA methylation: its role in cancer development and therapy

C Kurkjian, S Kummar, AJ Murgo - Current problems in cancer, 2008 - ncbi.nlm.nih.gov
Changes in the genome which result in cancer promotion remain a complex interplay of
aberrant methylation in the setting of a multitude of epigenetic changes. The events leading …

[HTML][HTML] Altered mucosal DNA methylation in parallel with highly active Helicobacter pylori-related gastritis

T Yoshida, J Kato, T Maekita, S Yamashita, S Enomoto… - Gastric Cancer, 2013 - Springer
Background Chronic inflammation triggered by Helicobacter pylori causes altered DNA
methylation in stomach mucosae, which is deeply involved in gastric carcinogenesis. This …

The presence of a methylation fingerprint of Helicobacter pylori infection in human gastric mucosae

T Nakajima, S Yamashita, T Maekita… - … journal of cancer, 2009 - Wiley Online Library
Aberrant DNA methylation is deeply involved in human cancers, but its inducers and targets
are still mostly unclear. Helicobacter pylori infection was recently shown to induce aberrant …

DNA methylation accumulation in gastric mucosa adjacent to cancer after Helicobacter pylori eradication

S Tahara, T Tahara, N Horiguchi, T Kato… - … Journal of Cancer, 2019 - Wiley Online Library
Molecular irreversibleness with Helicobacter pylori (H. pylori) infection might have a role in
gastric tumorigenesis after H. pylori eradication. We performed comprehensive DNA …

Inflammatory Processes Triggered by Helicobacter pylori Infection Cause Aberrant DNA Methylation in Gastric Epithelial Cells

T Niwa, T Tsukamoto, T Toyoda, A Mori, H Tanaka… - Cancer research, 2010 - AACR
Altered patterns of DNA methylation associated with Helicobacter pylori (HP) infection of
gastric epithelial cells are thought to contribute to gastric cancer risk. However, it is unclear …

Genome‐Wide DNA Methylation Profiles in Noncancerous Gastric Mucosae with Regard to Helicobacter pylori Infection and the Presence of Gastric Cancer

CM Shin, N Kim, Y Jung, JH Park, GH Kang… - …, 2011 - Wiley Online Library
Abstract Background and Aims: To determine genome‐wide DNA methylation profiles
induced by Helicobacter pylori (H. pylori) infection and to identify methylation markers in H …

High Levels of Aberrant DNA Methylation in Helicobacter pylori–Infected Gastric Mucosae and its Possible Association with Gastric Cancer Risk

T Maekita, K Nakazawa, M Mihara, T Nakajima… - Clinical Cancer …, 2006 - AACR
Introduction: Risk prediction of gastric cancers is important to implement appropriate
screening procedures. Although aberrant DNA methylation is deeply involved in gastric …

[HTML][HTML] DNA methylation: a marker for carcinogen exposure and cancer risk

T Nakajima, S Enomoto, T Ushijima - Environmental health and preventive …, 2008 - Springer
Cancers arise as a consequence of multiple genetic and epigenetic alterations. Many genes
aberrantly methylated in cancers have been identified in recent years, and their use in …

[HTML][HTML] Helicobacter pylori induces hypermethylation of CpG islands through upregulation of DNA methyltransferase: possible involvement of reactive oxygen …

HK Na, JH Woo - Journal of Cancer Prevention, 2014 - ncbi.nlm.nih.gov
Helicobacter pylori infection has been considered to be one of the major factors implicated
in etiology of gastric cancer. Aberrant DNA methylation accounts for epigenetic modifications …

DNA methylation in health, disease, and cancer

DS Shames, JD Minna… - Current molecular …, 2007 - ingentaconnect.com
The spatial arrangement and three-dimensional structure of DNA in the nucleus is controlled
through the interdigitation of DNA binding proteins such as histones and their modifiers, the …