The interest in midazolam as a sedative for pediatric patients has continued to increase.
Clinical and pharmacokinetic studies are further refining doses and routes of administration …

Dosing of midazolam in neonates Page 1 Special 30th Anniversary paper COMMENTARY
Dosing of midazolam in neonates T. Girard MD Department of Anesthesia, University …

Midazolam is a benzodiazepine with rapid onset of action and short duration of effect. In
healthy neonates the half‐life (t1/2) and the clearance (Cl) are 3.3‐fold longer and 3.7‐fold …

One of the most widely used options for minimal/moderate sedation in pediatric patients is
oral midazolam, as it presents an alternative to less well‐accepted routes of administration …

Objective: To evaluate the effects of intravenous midazolam on haemodynamic variables
and cerebral blood flow velocity (CBFV) and to determine the pharmacokinetics using a …

Objective: To determine efficacy of midazolam as a sedative in mechanically ventilated
newborns. Design: Double blind randomized placebo controlled trial. Setting: Neonatal Unit …

Our aim was to characterize effectiveness and complications in children receiving oral
midazolam alone, nasal midazolam alone, or oral midazolam with other sedatives. Children …

A variety of developmental changes is of influence on the pharmacokinetics and
pharmacodynamics of midazolam in neonatal and pediatric intensive care patients …

Sedation of intubated spontaneously breathing children in the pediatric intensive care unit is
desirable yet often difficult to achieve. A technique for providing consistent sedation in this …

PR240: Evaluation of the Efficacy of An Innovative... : Anesthesia & Analgesia Abstract PR240:
Evaluation of the Efficacy of An Innovative Oral Formulation of Midazolam for Moderate …