The transformation of the model organism: a decade of developmental genetics

KV Anderson, PW Ingham - Nature genetics, 2003 - nature.com
The past decade has seen the development of powerful techniques to dissect the molecular
processes that regulate development. New tools have been used to reveal the basis of cell …

Genetic Screen for Postembryonic Development in the Zebrafish (Danio rerio): Dominant Mutations Affecting Adult Form

K Henke, JM Daane, MB Hawkins, CM Dooley… - Genetics, 2017 - academic.oup.com
Large-scale forward genetic screens have been instrumental for identifying genes that
regulate development, homeostasis, and regeneration, as well as the mechanisms of …

Combined haploid and insertional mutation screen in the zebrafish

E Wiellette, Y Grinblat, M Austen, E Hirsinger… - genesis, 2004 - Wiley Online Library
To identify genes required for development of the brain and somites, we performed a pilot
screen of gynogenetic haploid zebrafish embryos produced from mothers mutagenized by …

[HTML][HTML] Zebrafish models of neurodevelopmental disorders: past, present, and future

C Sakai, S Ijaz, EJ Hoffman - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Zebrafish are increasingly being utilized as a model system to investigate the function of the
growing list of risk genes associated with neurodevelopmental disorders. This is due in large …

The neurogenetic frontier—lessons from misbehaving zebrafish

HA Burgess, M Granato - Briefings in Functional Genomics and …, 2008 - academic.oup.com
One of the central questions in neuroscience is how refined patterns of connectivity in the
brain generate and monitor behavior. Genetic mutations can influence neural circuits by …

Zebrafish genetics: the enigma of arrival

MC Fishman - Proceedings of the National Academy of …, 1999 - National Acad Sciences
The zebrafish (Danio rerio) has arrived in the pantheon of genetic model organisms.
Perched next to the mouse in the vertebrate alcove of the hall of metazoans, the zebrafish …

Zebrafish as a neurotoxicological model

E Linney, L Upchurch, S Donerly - Neurotoxicology and teratology, 2004 - Elsevier
At a time when common regulatory pathways are being identified in several different species
and genomics is beginning to allow comparisons of genes, how they are arranged on …

[引用][C] Patterning the brain of the zebrafish embryo

CB Kimmel - Annual review of neuroscience, 1993 - annualreviews.org
This review discusses how brain morphogenesis is related to the arrange ments of the
earliest neurons and their axons in a simple vertebrate, the zebrafish Brachydanio rerio …

[引用][C] Appendix 1 Genetic Backgrounds and Some Standard Stocks and Strains Used in Zebrafish Developmental Biology and Genetics

SL Johnson, LI Zon - Methods in cell biology, 1998 - Elsevier
Several different strains and stocks of zebrafish are available for developmental analysis
and genetic mapping. We may consider these different strains or stocks in two groups. The …

[图书][B] The zebrafish: biology

HW Detrich, M Westerfield, LI Zon - 1999 - books.google.com
This is the first in a two-volume, comprehensive treatment of the methodologies used in
researching the Zebrafish, an emerging vertebrate model system. The text includes …