Aberrant epithelial cell growth in autosomal dominant polycystic kidney disease

PD Wilson - American journal of kidney diseases, 1991 - Elsevier
Renal cyst enlargement in autosomal dominant polycystic kidney disease (ADPKD) is
characterized by increased epithelial cell proliferation and fluid accumulation. Using …

Abnormal extracellular matrix and excessive growth of human adult polycystic kidney disease epithelia

PD Wilson, D Hreniuk, PA Gabow - Journal of cellular …, 1992 - Wiley Online Library
Human autosomal dominant polycystic kidney disease (ADPKD) epithelia were grown in
primary monolayer cultures and their properties compared with intact kidney epithelial …

Autocrine, endocrine and paracrine regulation of growth abnormalities in autosomal dominant polycystic kidney disease.

PD Wilson, J Du, JT Norman - European journal of cell biology, 1993 - europepmc.org
Genetic polycystic kidney disease (ADPKD) is an autosomal dominant trait in man, the
phenotypic expression of which is characterized by enormous cystic enlargement of renal …

Impaired tubulogenesis of cyst-derived cells from autosomal dominant polycystic kidneys

FA Carone, S Nakamura, R Bacallao, WJ Nelson… - Kidney international, 1995 - Elsevier
Impaired tubulogenesis of cyst-derived cells from autosomal dominant polycystic kidneys.
Under appropriate growth factor or hormonal influence, renal epithelial cells cultured in …

Cyst formation and growth in autosomal dominant polycystic kidney disease

JJ Grantham, JL Geiser, AP Evan - Kidney international, 1987 - Elsevier
Cyst formation and growth in autosomal dominant polycystic kidney disease. Previous
morphologic studies on kidneys from adult patients with autosomal dominant polycystic …

Polycystic kidney disease: primary extracellular matrix abnormality or defective cellular differentiation?

JP Calvet - Kidney international, 1993 - Elsevier
Polycystic kidney disease: Primary extracellular matrix abnormality or defective cellular
differentiation? Polycystic kidney disease (PKD) is inherited as a dominant or recessive trait …

Endothelial dysfunction and angiogenesis in autosomal dominant polycystic kidney disease

GM Fick-Brosnahan - Current hypertension reviews, 2013 - ingentaconnect.com
Autosomal dominant polycystic kidney disease (ADPKD) is the most common potentially
lethal hereditary disease. The hall mark of the disease is the development of innumerable …

Plasticity of epithelial cells derived from human normal and ADPKD kidneys in primary cultures

G Elberg, S Guruswamy, CJ Logan, L Chen… - Cell and tissue …, 2008 - Springer
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by cyst formation
initiated by dedifferentiation and proliferation of renal tubular epithelial cells. Renal tubular …

Cyst fluid from human autosomal dominant polycystic kidneys promotes cyst formation and expansion by renal epithelial cells in vitro.

M Ye, M Grant, M Sharma, L Elzinga… - Journal of the …, 1992 - journals.lww.com
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive
renal enlargement, culminating in renal insufficiency in over one half of affected individuals …

Increased epithelial cell proliferation and abnormal extracellular matrix in rat polycystic kidney disease.

K Ramasubbu, N Gretz… - Journal of the American …, 1998 - journals.lww.com
Proliferation of renal tubular epithelial cells is considered a major factor leading to cyst
formation in human polycystic kidney disease (PKD). The Han: SPRD rat model for inherited …