When the human beta-globin gene was methylated at every cytosine residue and was
inserted into mouse fibroblasts by DNA-mediated gene transfer, the transcription of the gene …

We have studied the effect of DNA methylation on human y-globin gene expression, using a
novel in vitro DNA methylation technique. With this method we have methylated specific …

The relationship between DNA methylation and differential expression of rabbit beta-like
globin genes was studied by using restriction enzymes that cleave the sequence CCGG but …

The enzymatic methylation of the 5'-flanking region of the mouse beta-globin (major) gene
containing putative regulatory regions has been investigated. In vitro methylation of this 368 …

The human beta-globin gene is expressed--but the human fetal (gamma) and embryonic
(epsilon) globin genes are not--in an induced mouse erythroleukemia cell line (M11-X) that …

Human gamma A‐globin genes with different patterns of methylation were synthesized in
vitro. These methylated constructs were transfected into mouse L cells and their expression …

We have investigated certain specific methylation sites of the chicken alpha-globin gene
cluster in DNA from embryonic and adult erythroid cells as well as from brain and sperm …

This report identifies l‐ethionine as an inducer of differentiation in murine erythroleukemia
cells. When Friend erythroleukemia cells are grown in the presence of 4 mM l‐ethionine …

Is DNA methylation a key element in the regulation of vertebrate gene expression, or does it
play a minor part? There is support for both views in the recent literature, for while it is now …

We have analyzed DNA modification in the human+/I-globin gene region at 17 cleavage
sites of restriction endonucleases which are unable to cleave DNA if 5-methylcytosine is …