CD49d expression in chronic lymphocytic leukemia: a prognostic parameter and a therapeutic target

P Bulian, G Gaidano, GD Poeta, V Gattei - 2008 - Taylor & Francis
Evaluation of: Shanafelt TD, Geyer SM, Bone ND et al.: CD49d expression is an
independent predictor of overall survival in patients with chronic lymphocytic leukaemia: a …

Relevance of CD49d protein expression as overall survival and progressive disease prognosticator in chronic lymphocytic leukemia

V Gattei, P Bulian, MI Del Principe… - Blood, The Journal …, 2008 - ashpublications.org
CD49d/α4-integrin is variably expressed in chronic lymphocytic leukemia (CLL). We
evaluated its relevance as independent prognosticator for overall survival and time to …

CD49d expression is an independent predictor of overall survival in patients with chronic lymphocytic leukaemia: a prognostic parameter with therapeutic potential

TD Shanafelt, SM Geyer, ND Bone… - British journal of …, 2008 - Wiley Online Library
In vitro studies have demonstrated that surface expression of CD49d on chronic lymphocytic
leukaemia (CLL) B cells facilitates leukaemic cell–stromal interactions by binding to …

[HTML][HTML] CD49d expression is an independent risk factor of progressive disease in early stage chronic lymphocytic leukemia

D Rossi, A Zucchetto, FM Rossi, D Capello… - …, 2008 - haematologica.org
Identification of prognosticators for Binet A chronic lymphocytic leukemia is important for
selecting patients with dismal prognosis. We analyzed CD49d expression in 140 …

High CD49d protein and mRNA expression predicts poor outcome in chronic lymphocytic leukemia

H Nückel, M Switala, CH Collins, L Sellmann… - Clinical …, 2009 - Elsevier
CD49d plays a critical role in leucocyte trafficking, activation and survival, and facilitates
interactions between leucocytes and stromal cells. Recent data give evidence for the …

[HTML][HTML] The prognostic value of CD49d expression in Turkish patients with chronic lymphocytic leukemia

A Uzay, T Toptaş, I Kaygusuz, E Ekşioğlu-demiralp… - 2012 - jag.journalagent.com
OBJECTIVE: The aim of this study was to assess the prognostic value of CD49d expression
in Turkish chronic lymphocytic leukemia patients. METHODS: Data for 118 patients from a …

[HTML][HTML] CD69 is independently prognostic in chronic lymphocytic leukemia: a comprehensive clinical and biological profiling study

G Del Poeta, MI Del Principe, A Zucchetto… - …, 2012 - ncbi.nlm.nih.gov
Background CD69 is expressed in several hemopoietic cells and is an early activation
marker in chronic lymphocytic leukemia. Chronic lymphocytic leukemia is a clinically …

Clinical significance of CD69 expression in chronic lymphocytic leukemia

G Del Poeta, MI Del Principe, P Bulian, C Simotti… - Blood, 2010 - Elsevier
Abstract 3574 Chronic lymphocytic leukemia (B-CLL) is a very heterogeneous disease with
some patients experiencing rapid disease progression and others living for years without …

High CD79b Expression Predicts a Poor Outcome in B-Cell Chronic Lymphocytic Leukemia (B-CLL).

G Del Poeta, MI Del Principe, A Zucchetto, F Buccisano… - Blood, 2008 - Elsevier
Download: Download high-res image (76KB) Download: Download full-size image The
immunoglobulin (Ig) beta protein (CD79b) dimerizes with Ig alpha (CD79a) to form the …

CD49d is an independent prognostic marker that is associated with CXCR4 expression in CLL

A Majid, TT Lin, G Best, K Fishlock, S Hewamana… - Leukemia research, 2011 - Elsevier
The world of chronic lymphocytic leukemia (CLL) research is awash with prognostic
markers. However, very few of the current group play a clearly defined role in the pathology …