The effect of ticagrelor on growth of small abdominal aortic aneurysms—a randomized controlled trial

A Wanhainen, K Mani, J Kullberg… - Cardiovascular …, 2020 - academic.oup.com
Aims To evaluate if ticagrelor, an effective platelet inhibitor without known non-responders,
could inhibit growth of small abdominal aortic aneurysms (AAAs). Methods and results In this …

Anti-platelet treatment of middle-sized abdominal aortic aneurysms

JS Lindholt, M Bjorck, JB Michel - Current vascular …, 2013 - ingentaconnect.com
The physiological transport in the aortic wall occurs mainly by centrifugal convection from
the lumen to the adventitia through the arterial wall. Enlargement of an abdominal aortic …

[HTML][HTML] Editor's choice–pharmaceutical management of small abdominal aortic aneurysms: a systematic review of the clinical evidence

VBC Kokje, JF Hamming, JHN Lindeman - European Journal of Vascular …, 2015 - Elsevier
Background Management of abdominal aortic aneurysms (AAAs) relies on surgical repair of
larger AAAs. Consequently medical interventions inhibiting AAA progression could greatly …

Pharmacotherapy in clinical trials for abdominal aortic aneurysms: A systematic review and meta-analysis

Z Su, J Guo, Y Gu - Clinical and Applied Thrombosis …, 2022 - journals.sagepub.com
Objective There is no medical treatment proven to limit abdominal aortic aneurysm (AAA)
progression. This systematic review aimed to summarise available trial evidence on the …

Multicentre study of abdominal aortic aneurysm measurement and enlargement

FA Lederle, S Noorbaloochi, S Nugent… - Journal of British …, 2015 - academic.oup.com
Background No effective treatment is currently available to prevent progression of small and
medium-sized abdominal aortic aneurysms (AAAs). Identification of drugs with sufficient …

[HTML][HTML] The efficacy of pharmacotherapy for decreasing the expansion rate of abdominal aortic aneurysms: a systematic review and meta-analysis

I Guessous, D Periard, D Lorenzetti, J Cornuz… - PLoS …, 2008 - journals.plos.org
Background Pharmacotherapy may represent a potential means to limit the expansion rate
of abdominal aortic aneurysms (AAAs). Studies evaluating the efficacy of different …

Growth rates of small abdominal aortic aneurysms assessed by computerised tomography–a systematic literature review

K Hendy, R Gunnarson, J Golledge - Atherosclerosis, 2014 - Elsevier
Background Most current evidence examining abdominal aortic aneurysm (AAA) growth is
based on ultrasound surveillance. Objective This review aimed to systematically analyse …

[HTML][HTML] Growth predictors and prognosis of small abdominal aortic aneurysms

FJV Schlösser, MJD Tangelder, HJM Verhagen… - Journal of vascular …, 2008 - Elsevier
OBJECTIVE: Evidence regarding the influence of cardiovascular risk factors, comorbidities,
and patient characteristics on the growth of small abdominal aortic aneurysms (AAA) is …

Efficacy of telmisartan to slow growth of small abdominal aortic aneurysms: a randomized clinical trial

J Golledge, J Pinchbeck, SM Tomee… - JAMA …, 2020 - jamanetwork.com
Importance Currently there is no drug therapy for abdominal aortic aneurysm (AAA).
Objective To test the efficacy of the angiotensin receptor blocker telmisartan in slowing AAA …

[HTML][HTML] Challenges and opportunities in limiting abdominal aortic aneurysm growth

J Golledge, PE Norman, MP Murphy… - Journal of vascular …, 2017 - Elsevier
Objective This review describes ongoing efforts to develop a medical therapy to limit
abdominal aortic aneurysm (AAA) growth. Methods Data from animal model studies, human …