Medical treatment for small abdominal aortic aneurysms

G Rughani, L Robertson… - Cochrane database of …, 2012 - cochranelibrary.com
Background Screening for abdominal aortic aneurysm (AAA) in selected groups is now
performed in England, the USA and Sweden. Patients with aneurysms over 55 mm in …

[HTML][HTML] Pharmacological interventions to attenuate the expansion of abdominal aortic aneurysm (AAA)–a systematic review

D Bergqvist - European Journal of Vascular and Endovascular …, 2011 - Elsevier
INTRODUCTION: Is it possible by pharmacological methods to attenuate the expansion rate
of abdominal aortic aneurysms? METHOD: An Internet-based systematic literature search …

Smaller size is more suitable for pharmacotherapy among undersized abdominal aortic aneurysm: A systematic review and meta-analysis

T Shirasu, H Takagi, J Yasuhara, T Kuno… - Vascular …, 2022 - journals.sagepub.com
Background: Pharmacotherapy for undersized abdominal aortic aneurysm (AAA) is a clinical
unmet need. Randomized controlled trials (RCTs) have failed to show effectiveness despite …

[HTML][HTML] Challenges and opportunities in limiting abdominal aortic aneurysm growth

J Golledge, PE Norman, MP Murphy… - Journal of vascular …, 2017 - Elsevier
Objective This review describes ongoing efforts to develop a medical therapy to limit
abdominal aortic aneurysm (AAA) growth. Methods Data from animal model studies, human …

[HTML][HTML] Metformin treatment status and abdominal aortic aneurysm disease progression

N Fujimura, J Xiong, EB Kettler, H Xuan… - Journal of vascular …, 2016 - Elsevier
Objective In population-based studies performed on multiple continents during the past two
decades, diabetes mellitus has been negatively associated with the prevalence and …

[HTML][HTML] The protective effect of metformin on abdominal aortic aneurysm: a systematic review and meta-analysis

Z Yuan, Z Heng, Y Lu, J Wei, Z Cai - Frontiers in Endocrinology, 2021 - frontiersin.org
Background Type 2 diabetes mellitus (T2DM) patients have a lower risk of abdominal aortic
aneurysm (AAA) and its comorbidities, which might be associated with the usage of …

Statin use and rupture of abdominal aortic aneurysm

H Wemmelund, A Høgh, HH Hundborg… - Journal of British …, 2014 - academic.oup.com
Background Ruptured abdominal aortic aneurysm (rAAA) is associated with high mortality.
Research suggests that statins may reduce abdominal aortic aneurysm (AAA) growth and …

Statin therapy reduces growth of abdominal aortic aneurysms

W Karrowni, S Dughman, GP Hajj… - Journal of …, 2011 - journals.sagepub.com
Background The aim of this study was to evaluate the influence of statins on the growth of
small abdominal aortic aneurysms (AAAs). Methods We retrospectively examined AAA …

Pharmacological treatment of abdominal aortic aneurysm

T Miyake, R Morishita - Cardiovascular research, 2009 - academic.oup.com
Abdominal aortic aneurysm (AAA) is a common degenerative condition with high mortality in
older men. Elective surgical or endovascular repair is performed to prevent rupture of large …

Abdominal aortic aneurysm: a review on the role of oral antidiabetic drugs.

M Ribeiro-Silva, J Oliveira-Pinto… - International angiology: a …, 2020 - europepmc.org
Conclusions Metformin seems to be associated with a decrease in AAA risk and
enlargement rate. Evidence for the other classes is lacking. Studies evaluating the …