Epigenetics: differential DNA methylation in mammalian somatic tissues
H Nagase, S Ghosh - The FEBS journal, 2008 - Wiley Online Library
Epigenetics refers to heritable phenotypic alterations in the absence of DNA sequence
changes, and DNA methylation is one of the extensively studied epigenetic alterations. DNA …
changes, and DNA methylation is one of the extensively studied epigenetic alterations. DNA …
Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation
Background Uncovering mechanisms of epigenome evolution is an essential step towards
understanding the evolution of different cellular phenotypes. While studies have confirmed …
understanding the evolution of different cellular phenotypes. While studies have confirmed …
The diverse roles of DNA methylation in mammalian development and disease
MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
DNA methylation is of paramount importance for mammalian embryonic development. DNA
methylation has numerous functions: it is implicated in the repression of transposons and …
methylation has numerous functions: it is implicated in the repression of transposons and …
DNA demethylation pathways: recent insights
C Li - Genetics & Epigenetics, 2013 - journals.sagepub.com
DNA methylation is a major epigenetic regulatory mechanism for gene expression and cell
differentiation. Until recently, it was still unclear how unmethylated regions in mammalian …
differentiation. Until recently, it was still unclear how unmethylated regions in mammalian …
Emerging concept in DNA methylation: role of transcription factors in shaping DNA methylation patterns
DNA methylation in mammals is a key epigenetic modification essential to normal genome
regulation and development. DNA methylation patterns are established during early …
regulation and development. DNA methylation patterns are established during early …
[HTML][HTML] Analysis of tissue-specific differentially methylated regions (TDMs) in humans
E Kitamura, J Igarashi, A Morohashi, N Hida, T Oinuma… - Genomics, 2007 - Elsevier
Alterations in DNA methylation have been implicated in mammalian development. Hence,
the identification of tissue-specific differentially methylated regions (TDMs) is indispensable …
the identification of tissue-specific differentially methylated regions (TDMs) is indispensable …
Parent-of-origin DNA methylation dynamics during mouse development
Y Stelzer, H Wu, Y Song, CS Shivalila, S Markoulaki… - Cell reports, 2016 - cell.com
Parent-specific differentially methylated regions (DMRs) are established during
gametogenesis and regulate parent-specific expression of imprinted genes. Monoallelic …
gametogenesis and regulate parent-specific expression of imprinted genes. Monoallelic …
[PDF][PDF] New insights on the role of DNA methylation from a global view
K Meier, F Recillas-Targa - Front Biosci (Landmark Ed), 2017 - article.imrpress.com
In mammals, DNA methylation is a crucial epigenetic modification with key functions during
development. Cellular processes that are regulated by DNA methylation comprise X …
development. Cellular processes that are regulated by DNA methylation comprise X …
Mechanisms of DNA methylation and demethylation during mammalian development
N Veland, T Chen - Handbook of Epigenetics, 2017 - Elsevier
DNA methylation, the addition of a methyl group at the 5-position of cytosine (5-
methylcytosine, 5mC), is a major epigenetic modification in the genomes of many animals …
methylcytosine, 5mC), is a major epigenetic modification in the genomes of many animals …
Conservation and divergence of DNA methylation in eukaryotes: new insights from single base-resolution DNA methylomes
DNA methylation is one of the most important heritable epigenetic modifications of the
genome and is involved in the regulation of many cellular processes. Aberrant DNA …
genome and is involved in the regulation of many cellular processes. Aberrant DNA …
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