Melatonin: a pleiotropic molecule regulating inflammation
Melatonin is a neurohormone produced by the pineal gland that regulates sleep and
circadian functions. Melatonin also regulates inflammatory and immune processes acting as …
circadian functions. Melatonin also regulates inflammatory and immune processes acting as …
Melatonin and inflammation—Story of a double‐edged blade
R Hardeland - Journal of pineal research, 2018 - Wiley Online Library
Melatonin is an immune modulator that displays both pro‐and anti‐inflammatory properties.
Proinflammatory actions, which are well documented by many studies in isolated cells or …
Proinflammatory actions, which are well documented by many studies in isolated cells or …
A review of the molecular aspects of melatonin's anti‐inflammatory actions: recent insights and new perspectives
Melatonin is a highly evolutionary conserved endogenous molecule that is mainly produced
by the pineal gland, but also by other nonendocrine organs, of most mammals including …
by the pineal gland, but also by other nonendocrine organs, of most mammals including …
Melatonin: Nature's most versatile biological signal?
SR Pandi‐Perumal, V Srinivasan… - The FEBS …, 2006 - Wiley Online Library
Melatonin is a ubiquitous molecule and widely distributed in nature, with functional activity
occurring in unicellular organisms, plants, fungi and animals. In most vertebrates, including …
occurring in unicellular organisms, plants, fungi and animals. In most vertebrates, including …
[HTML][HTML] Melatonin: buffering the immune system
A Carrillo-Vico, PJ Lardone… - International journal of …, 2013 - mdpi.com
Melatonin modulates a wide range of physiological functions with pleiotropic effects on the
immune system. Despite the large number of reports implicating melatonin as an …
immune system. Despite the large number of reports implicating melatonin as an …
[HTML][HTML] Melatonin: exceeding expectations
Melatonin is a small, highly conserved indole with numerous receptor-mediated and
receptor-independent actions. Receptor-dependent functions include circadian rhythm …
receptor-independent actions. Receptor-dependent functions include circadian rhythm …
Role of melatonin in the inflammatory process and its therapeutic potential
Melatonin is an indolamine synthesized and secreted by the pineal gland along with other
extrapineal sources including immune system cells, the brain, skin and the gastrointestinal …
extrapineal sources including immune system cells, the brain, skin and the gastrointestinal …
Melatonin as an anti‐inflammatory agent modulating inflammasome activation
G Favero, L Franceschetti, F Bonomini… - International journal …, 2017 - Wiley Online Library
Inflammation may be defined as the innate response to harmful stimuli such as pathogens,
injury, and metabolic stress; its ultimate function is to restore the physiological homeostatic …
injury, and metabolic stress; its ultimate function is to restore the physiological homeostatic …
Melatonin and its relation to the immune system and inflammation
Melatonin (N‐acetyl‐5‐methoxytryptamine) was initially thought to be produced exclusively
in the pineal gland. Subsequently its synthesis was demonstrated in other organs, for …
in the pineal gland. Subsequently its synthesis was demonstrated in other organs, for …
Pleiotropic effects of melatonin
D Mahmood - Drug research, 2019 - thieme-connect.com
Melatonin's pleiotropic actions begin from controlling day/night cycle and
hypothalamic/pituitary axes to, for example, vasomotor effects, immunomodulation, antilipid …
hypothalamic/pituitary axes to, for example, vasomotor effects, immunomodulation, antilipid …