Background As the overdose crisis in Canada continues to escalate in severity, novel
interventions and programs are required. Safer Supply programs offer pharmaceutical-grade …

Drug overdose deaths in the United States have more than doubled since 1999 (1). During
2013, 43,982 drug overdose deaths (unintentional, intentional [suicide or homicide], or …

BACKGROUND: In response to the high rates of opiate-related overdoses and deaths in the
United States, a number of overdose prevention programmes have been implemented that …

Heroin overdose deaths have increased alarmingly in Chicago over the past decade.
Naloxone, an opioid antagonist with no abuse potential, has been used to reverse opiate …

Background Opioid overdose is a leading cause of death among injection drug users. Over
half of injection drug users report at least one nonfatal overdose during their lifetime. Death …

Background As several regulatory and environmental changes have occurred in North
America, trends in overdose deaths were examined in the United States (US), Ontario and …

Opiate overdose persists as a major public health problem, contributing to significant
morbidity and mortality among opiate users globally. Opiate overdose can be reversed by …

Strategies for Reducing Opioid-Overdose Deaths — Lessons from Canada | New England Journal
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

The opioid use and overdose crisis is persistent and dynamic. Opioid overdoses were
initially driven in the 1990s and 2000s by the increasing availability and misuse of …

Opioids are potent respiratory depressants, and overdose is a leading cause of death
among people who use them. Worldwide, an estimated 69 000 people die from opioid …