[HTML][HTML] Cognition and neuropsychological changes at altitude—A systematic review of literature

K Bliemsrieder, EM Weiss, R Fischer, H Brugger… - Brain Sciences, 2022 - mdpi.com
High-altitude (HA) exposure affects cognitive functions, but studies have found inconsistent
results. The aim of this systematic review was to evaluate the effects of HA exposure on …

[HTML][HTML] Cytomorphometric changes in hippocampal CA1 neurons exposed to simulated microgravity using rats as model

A Ranjan, J Behari, BN Mallick - Frontiers in Neurology, 2014 - frontiersin.org
Microgravity and sleep loss lead to cognitive and learning deficits. These behavioral
alterations are likely to be associated with cytomorphological changes and loss of neurons …

[HTML][HTML] Domain specific changes in cognition at high altitude and its correlation with hyperhomocysteinemia

VK Sharma, SK Das, P Dhar, KB Hota, BB Mahapatra… - PLoS …, 2014 - journals.plos.org
Though acute exposure to hypobaric hypoxia is reported to impair cognitive performance,
the effects of prolonged exposure on different cognitive domains have been less studied …

Possible role of a dual regulator of neuroinflammation and autophagy in a simulated space environment

S Zhao, S Pei, A Wang, Y Chen, P Zhang, B Li… - Acta Astronautica, 2021 - Elsevier
Radiation and microgravity exert different biological effects on the human brain during space
flight. Studies rarely focus on the two combined. The central nervous system (CNS) is among …

[HTML][HTML] Spaceflight induces oxidative damage to blood-brain barrier integrity in a mouse model

XW Mao, NC Nishiyama, SD Byrum… - … : official publication of …, 2020 - ncbi.nlm.nih.gov
Many factors contribute to the health risks encountered by astronauts on missions outside
Earth's atmosphere. Spaceflight-induced potential adverse neurovascular damage and late …

Cerebral circulation and brain

PN Ainslie, MH Wilson, CHE Imray - High Altitude: Human Adaptation to …, 2013 - Springer
It should be noted that Dr. JW Severinghaus was the expert author of this chapter (Cerebral
circulation at high altitude) in the First Edition of this textbook. Moreover, in updating this …

[HTML][HTML] The human brain in a high altitude natural environment: A review

X Zhang, J Zhang - Frontiers in Human Neuroscience, 2022 - frontiersin.org
With the advancement of in vivo magnetic resonance imaging (MRI) technique, more
detailed information about the human brain at high altitude (HA) has been revealed. The …

Effect of hypoxia on the morphology of mouse striatal neurons

MG Wallace, KD Hartle, WM Snow, NL Ward, TL Ivanco - Neuroscience, 2007 - Elsevier
Symptoms of high altitude sickness including headache and neuropsychological dysfunction
are thought to result from prolonged exposure to hypoxia. In order to explain how the brain …

[HTML][HTML] Time-course adaptive changes in hippocampal transcriptome and synaptic function induced by simulated microgravity associated with cognition

R Liang, L Wang, Q Yang, Q Xu, S Sun… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction The investigation of cognitive function in microgravity, both short-term and long-
term, remains largely descriptive. And the underlying mechanisms of the changes over time …

[HTML][HTML] High-altitude cognitive impairment is prevented by enriched environment including exercise via VEGF signaling

C Koester-Hegmann, H Bengoetxea… - Frontiers in cellular …, 2019 - frontiersin.org
Exposure to hypobaric hypoxia at high altitude (above 2500 m asl) causes cognitive
impairment, mostly attributed to changes in brain perfusion and consequently neuronal …