The methyl-CpG binding domain (MBD) of the transcriptional repressor MeCP2 has been
proposed to recognize a single symmetrically methylated CpG base pair via hydrophobic …

Mutations in the X-linked gene encoding methyl-CpG–binding protein 2 (MeCP2) cause Rett
syndrome (RTT), a neurological disorder affecting cognitive development, respiration, and …

DNA methylation is implicated in neuronal biology via the protein MeCP2, the mutation of
which causes Rett syndrome. MeCP2 recruits the NCOR1/2 co-repressor complexes to …

Methyl-CpG-binding protein 2 is a characteristic member of the methyl-CpG–binding protein
family of transcription regulators. In conjunction with Sin3, MeCP2 recruits class I histone …

Rett syndrome is a neurological, X chromosomal-linked disorder associated with mutations
in the MECP2 gene. MeCP2 protein has been proposed to play a role in transcriptional …

More than 90% of Rett syndrome (RTT) patients have heterozygous mutations in the X‐
linked methyl‐CpG binding protein 2 (MECP2) gene that encodes the methyl‐CpG‐binding …

Mutations in the X-linked gene MECP2 (methyl CpG-binding protein 2) are the primary
cause of the neurodevelopmental disorder RTT (Rett syndrome), and are also implicated in …

Rett Syndrome is a severe neurological disorder mainly due to de novo mutations in the
methyl-CpG-binding protein 2 gene (MECP2). Mecp2 is known to play a role in chromatin …

The role of epigenetics in human disease has become an area of increased research
interest. Collaborative efforts from scientists and clinicians have led to a better …

Mutations of X-linked gene Methyl CpG binding protein 2 (MECP2) are the major causes of
Rett syndrome (RTT), a severe neurodevelopmental disorder. Duplications of MECP2 …