Cerebral metabolic rate of oxygen (CMRO2) is an important marker for brain function and
brain health. Existing techniques for quantification of CMRO2 with positron emission …

Purpose To assess the reproducibility of blood oxygenation level‐dependent/cerebral blood
flow (BOLD/CBF) responses to hypercapnia/hyperoxia using dual‐echo pseudo‐continuous …

A quantitative estimate of cerebral blood oxygen saturation is of critical importance in the
investigation of cerebrovascular disease because of the fact that it could potentially provide …

Calibrated functional magnetic resonance imaging (fMRI) provides a noninvasive technique
to assess functional metabolic changes associated with normal aging. We simultaneously …

New MRI methods for noninvasive imaging of baseline oxygen extraction fraction (OEF) in
the brain show great promise. Quantitative O 2 imaging (QUO2) applies a biophysical model …

The effect of the basal cerebral blood flow (CBF) on both the magnitude and dynamics of the
functional hemodynamic response in humans has not been fully investigated. Thus, the …

PURPOSE To quantitate the amplitude changes and temporal dynamics of regional
functional MR imaging signals during voluntary hyperventilation using blood oxygen level …

The development of neuroimaging methods to characterize flow-metabolism coupling is
crucial for understanding mechanisms that subserve oxygen delivery. Functional magnetic …

The physiological basis of the blood oxygenation level dependent (BOLD) signal and its
dependence on baseline cerebral blood flow (CBF) were investigated by comparing …

Cerebrovascular reactivity (CVR) reflects the capacity of blood vessels to dilate and is an
important marker for brain vascular reserve. It may provide a useful addition to the traditional …