CBF, BOLD, CBV, and CMRO2 fMRI signal temporal dynamics at 500‐msec resolution

Q Shen, H Ren, TQ Duong - … Imaging: An Official Journal of the …, 2008 - Wiley Online Library
Purpose To investigate the temporal dynamics of blood oxygenation level‐dependent
(BOLD), cerebral blood flow (CBF), cerebral blood volume (CBV), and cerebral metabolic …

Biophysical and physiological origins of blood oxygenation level-dependent fMRI signals

SG Kim, S Ogawa - Journal of Cerebral Blood Flow & …, 2012 - journals.sagepub.com
After its discovery in 1990, blood oxygenation level-dependent (BOLD) contrast in functional
magnetic resonance imaging (fMRI) has been widely used to map brain activation in …

Comparison of the effects of independently‐controlled end‐tidal PCO2 and PO2 on blood oxygen level–dependent (BOLD) MRI

E Prisman, M Slessarev, J Han… - Journal of Magnetic …, 2008 - Wiley Online Library
Purpose To assess the effect of changes in end‐tidal partial pressure of O2 (PetO2) on
cerebrovascular reactivity (CVR) estimated from changes in blood oxygen level–dependent …

Modeling of dynamic cerebrovascular reactivity to spontaneous and externally induced CO2 fluctuations in the human brain using BOLD-fMRI

PC Prokopiou, KTS Pattinson, RG Wise, GD Mitsis - Neuroimage, 2019 - Elsevier
In this work, we investigate the regional characteristics of the dynamic interactions between
arterial CO 2 and BOLD (dynamic cerebrovascular reactivity-dCVR) during normal breathing …

Multiparametric measurement of cerebral physiology using calibrated fMRI

MG Bright, PL Croal, NP Blockley, DP Bulte - Neuroimage, 2019 - Elsevier
The ultimate goal of calibrated fMRI is the quantitative imaging of oxygen metabolism
(CMRO 2), and this has been the focus of numerous methods and approaches. However …

Evaluation of MR-derived cerebral oxygen metabolic index in experimental hyperoxic hypercapnia, hypoxia, and ischemia

H An, Q Liu, Y Chen, W Lin - Stroke, 2009 - Am Heart Assoc
Background and Purpose—A noninvasive MRI method to measure cerebral oxygen
metabolism has the potential to assess tissue viability during cerebral ischemia. The …

[HTML][HTML] A practical modification to a resting state fMRI protocol for improved characterization of cerebrovascular function

RC Stickland, KM Zvolanek, S Moia, A Ayyagari… - Neuroimage, 2021 - Elsevier
Cerebrovascular reactivity (CVR), defined here as the Blood Oxygenation Level Dependent
(BOLD) response to a CO 2 pressure change, is a useful metric of cerebrovascular function …

Blood‐oxygen level dependent MRI measures of cerebrovascular reactivity using a controlled respiratory challenge: reproducibility and gender differences

A Kassner, JD Winter, J Poublanc… - Journal of Magnetic …, 2010 - Wiley Online Library
Purpose: To evaluate the reproducibility and gender differences in cerebrovascular reactivity
(CVR) measurements obtained using the blood‐oxygen level dependent (BOLD) response …

Effect of respiratory CO2 changes on the temporal dynamics of the hemodynamic response in functional MR imaging

LJ Kemna, S Posse - Neuroimage, 2001 - Elsevier
Increasing end-expiratory CO2 levels (PETCO2) increases the dispersion and the time of
maximum of the hemodynamic response curve in human primary visual cortex. This was …

Estimating cerebral oxygen metabolism from fMRI with a dynamic multicompartment Windkessel model

TJ Huppert, MS Allen, SG Diamond… - Human brain …, 2009 - Wiley Online Library
Stimulus evoked changes in cerebral blood flow, volume, and oxygenation arise from
responses to underlying neuronally mediated changes in vascular tone and cerebral oxygen …