Estimating cerebral oxygen metabolism from fMRI with a dynamic multicompartment Windkessel model
TJ Huppert, MS Allen, SG Diamond… - Human brain …, 2009 - Wiley Online Library
Stimulus evoked changes in cerebral blood flow, volume, and oxygenation arise from
responses to underlying neuronally mediated changes in vascular tone and cerebral oxygen …
responses to underlying neuronally mediated changes in vascular tone and cerebral oxygen …
Comparing cerebrovascular reactivity measured using BOLD and cerebral blood flow MRI: The effect of basal vascular tension on vasodilatory and vasoconstrictive …
S Halani, JB Kwinta, AM Golestani, YB Khatamian… - Neuroimage, 2015 - Elsevier
Cerebrovascular reactivity (CVR) is an important metric of cerebrovascular health. While the
BOLD fMRI method in conjunction with carbon-dioxide (CO 2) based vascular manipulation …
BOLD fMRI method in conjunction with carbon-dioxide (CO 2) based vascular manipulation …
Cerebral metabolic rate of oxygen (CMRO2) mapping with hyperventilation challenge using quantitative susceptibility mapping (QSM)
J Zhang, D Zhou, TD Nguyen… - Magnetic resonance …, 2017 - Wiley Online Library
Purpose Our objective was to demonstrate the feasibility of using hyperventilation as an
efficient vasoconstrictive challenge and prior knowledge as denoising constraints for …
efficient vasoconstrictive challenge and prior knowledge as denoising constraints for …
Reproducibility of BOLD, perfusion, and CMRO2 measurements with calibrated-BOLD fMRI
O Leontiev, RB Buxton - Neuroimage, 2007 - Elsevier
The coupling of changes in cerebral blood flow (CBF) and cerebral metabolic rate of oxygen
(CMRO2) during brain activation can be characterized by an empirical index, n, defined as …
(CMRO2) during brain activation can be characterized by an empirical index, n, defined as …
Relation between regional functional MRI activation and vascular reactivity to carbon dioxide during normal aging
Recent blood oxygenation level–dependent (BOLD) functional magnetic resonance imaging
studies have shown a reduction of cerebral activation during aging, which may be …
studies have shown a reduction of cerebral activation during aging, which may be …
Characterization of cerebrovascular responses to hyperoxia and hypercapnia using MRI in rat
J Lu, G Dai, Y Egi, S Huang, SJ Kwon, EH Lo, YR Kim - Neuroimage, 2009 - Elsevier
Understanding cerebrovascular responses to hyperoxia and hypercapnia is important for
investigating exogenous regulation of cerebral hemodynamics. We characterized gas …
investigating exogenous regulation of cerebral hemodynamics. We characterized gas …
A general analysis of calibrated BOLD methodology for measuring CMRO2 responses: comparison of a new approach with existing methods
The amplitude of the BOLD response to a stimulus is not only determined by changes in
cerebral blood flow (CBF) and oxygen metabolism (CMRO2), but also by baseline …
cerebral blood flow (CBF) and oxygen metabolism (CMRO2), but also by baseline …
Non-Invasive Measurement of Cerebral Oxygen Metabolism in the Mouse Brain by Ultra-High Field 17O MR Spectroscopy
W Cui, XH Zhu, ML Vollmers… - Journal of Cerebral …, 2013 - journals.sagepub.com
To assess cerebral energetics in transgenic mouse models of neurologic disease, a robust,
efficient, and practical method for quantification of cerebral oxygen consumption is needed …
efficient, and practical method for quantification of cerebral oxygen consumption is needed …
Baseline blood oxygenation modulates response amplitude: physiologic basis for intersubject variations in functional MRI signals
Abstract Although BOLD functional MRI (fMRI) provides a useful tool for probing neuronal
activities, large intersubject variations in signal amplitude are commonly observed …
activities, large intersubject variations in signal amplitude are commonly observed …
Quantitative measurement of cerebral physiology using respiratory-calibrated MRI
Functional magnetic resonance imaging typically measures signal increases arising from
changes in the transverse relaxation rate over small regions of the brain and associates …
changes in the transverse relaxation rate over small regions of the brain and associates …