The effect of basal vasodilation on hypercapnic and hypocapnic reactivity measured using magnetic resonance imaging

MG Bright, MJ Donahue, JH Duyn… - Journal of Cerebral …, 2011 - journals.sagepub.com
Cerebrovascular reactivity to vasodilatory hypercapnic and vasoconstrictive hypocapnic
challenges is known to be altered in several hemodynamic disorders, which is often …

Approaches to brain stress testing: BOLD magnetic resonance imaging with computer-controlled delivery of carbon dioxide

WAC Mutch, DM Mandell, JA Fisher, DJ Mikulis… - PLoS …, 2012 - journals.plos.org
Background An impaired vascular response in the brain regionally may indicate reduced
vascular reserve and vulnerability to ischemic injury. Changing the carbon dioxide (CO2) …

[HTML][HTML] The association between BOLD-based cerebrovascular reactivity (CVR) and end-tidal CO2 in healthy subjects

X Hou, P Liu, Y Li, D Jiang, B Jill, Z Lin, S Sur, Z Baker… - Neuroimage, 2020 - Elsevier
Cerebrovascular reactivity (CVR) mapping using CO 2-inhalation can provide important
insight into vascular health. At present, blood-oxygenation-level-dependent (BOLD) MRI …

The Cumulative Influence of Hyperoxia and Hypercapnia on Blood Oxygenation and R2*

CC Faraco, MK Strother, JCW Siero… - Journal of Cerebral …, 2015 - journals.sagepub.com
Cerebrovascular reactivity (CVR)-weighted blood-oxygenation-level-dependent magnetic
resonance imaging (BOLD-MRI) experiments are frequently used in conjunction with …

Regional dynamic signal changes during controlled hyperventilation assessed with blood oxygen level-dependent functional MR imaging.

S Posse, U Olthoff, M Weckesser… - American journal …, 1997 - Am Soc Neuroradiology
PURPOSE To quantitate the amplitude changes and temporal dynamics of regional
functional MR imaging signals during voluntary hyperventilation using blood oxygen level …

Quantitative measurement of cerebral physiology using respiratory-calibrated MRI

DP Bulte, M Kelly, M Germuska, J Xie, MA Chappell… - Neuroimage, 2012 - Elsevier
Functional magnetic resonance imaging typically measures signal increases arising from
changes in the transverse relaxation rate over small regions of the brain and associates …

Regional cerebrovascular responses to hypercapnia and hypoxia

DR Corfield, LC McKay - Hypoxia: Translation in Progress, 2016 - Springer
A limited number of studies using differing imaging approaches suggest that there are
regional variation in the cerebrovascular response to hypercapnia and hypoxia. However …

Measurement of cerebral blood volume in humans using hyperoxic MRI contrast

D Bulte, P Chiarelli, R Wise… - Journal of Magnetic …, 2007 - Wiley Online Library
Purpose To develop a new method of measuring quantitative regional cerebral blood
volume (CBV) using epochs of hyperoxia as an intravenous contrast agent with T2 …

Regional cerebral blood volume response to hypocapnia using susceptibility contrast MRI

JF Payen, E Briot, I Tropres… - NMR in …, 2000 - Wiley Online Library
We used steady‐state susceptibility contrast MRI to evaluate the regional cerebral blood
volume (rCBV) response to hypocapnia in anesthetised rats. The rCBV was determined in …

The impact of inspired oxygen levels on calibrated fMRI measurements of M, OEF and resting CMRO2 using combined hypercapnia and hyperoxia

I Lajoie, FB Tancredi, RD Hoge - PLoS One, 2017 - journals.plos.org
Recent calibrated fMRI techniques using combined hypercapnia and hyperoxia allow the
mapping of resting cerebral metabolic rate of oxygen (CMRO2) in absolute units, oxygen …