Changes in T1 and T2 observed in brain magnetic resonance imaging with delivery of high concentrations of oxygen

H Uematsu, M Takahashi, H Hatabu… - Journal of computer …, 2007 - journals.lww.com
Objective: The aim of this study was to clarify the relative contributions of the amount of
oxygen in the blood, and vasoconstriction/dilation responsible for changes in T1 and T2 …

Characterization of regional heterogeneity in cerebrovascular reactivity dynamics using novel hypocapnia task and BOLD fMRI

MG Bright, DP Bulte, P Jezzard, JH Duyn - Neuroimage, 2009 - Elsevier
We offer a new method for characterizing the magnitude and dynamics of the vascular
response to changes in arterial gas tensions using non-invasive blood oxygenation level …

Cerebrovascular reactivity by quantitative magnetic resonance angiography with a Co2 challenge. Validation as a new imaging biomarker

L Caputi, F Ghielmetti, G Faragò, F Longaretti… - European Journal of …, 2014 - Elsevier
Assessment of cerebrovascular reactivity (CVR) is essential in cerebrovascular diseases, as
exhausted CVR may enhance the risk of cerebral ischemic events. Transcranial Doppler …

CVR-MRICloud: An online processing tool for CO2-inhalation and resting-state cerebrovascular reactivity (CVR) MRI data

P Liu, Z Baker, Y Li, Y Li, J Xu, DC Park, BG Welch… - PloS one, 2022 - journals.plos.org
Cerebrovascular Reactivity (CVR) provides an assessment of the brain's vascular reserve
and has been postulated to be a sensitive marker in cerebrovascular diseases. MRI-based …

[HTML][HTML] A practical modification to a resting state fMRI protocol for improved characterization of cerebrovascular function

RC Stickland, KM Zvolanek, S Moia, A Ayyagari… - Neuroimage, 2021 - Elsevier
Cerebrovascular reactivity (CVR), defined here as the Blood Oxygenation Level Dependent
(BOLD) response to a CO 2 pressure change, is a useful metric of cerebrovascular function …

Regional quantification of cerebral venous oxygenation from MRI susceptibility during hypercapnia

AP Fan, KC Evans, JN Stout, BR Rosen… - Neuroimage, 2015 - Elsevier
There is an unmet medical need for noninvasive imaging of regional brain oxygenation to
manage stroke, tumor, and neurodegenerative diseases. Oxygenation imaging from …

[HTML][HTML] Suppl 1: The Relationship Between M in “Calibrated fMRI” and the Physiologic Modulators of fMRI

H Lu, J Hutchison, F Xu, B Rypma - The open neuroimaging …, 2011 - ncbi.nlm.nih.gov
The “calibrated fMRI” technique requires a hypercapnia calibration experiment in order to
estimate the factor “M”. It is desirable to be able to obtain the M value without the need of a …

Cerebral OEF quantification: A comparison study between quantitative susceptibility mapping and dual‐gas calibrated BOLD imaging

Y Ma, H Sun, J Cho, EL Mazerolle… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose To compare regional oxygen extraction fraction (OEF) and cerebral metabolic rate
of oxygen consumption (CMRO2) quantified from the microvascular quantitative …

Dynamics of changes in blood flow, volume, and oxygenation: implications for dynamic functional magnetic resonance imaging calibration

I Kida, DL Rothman, F Hyder - Journal of Cerebral Blood …, 2007 - journals.sagepub.com
Changes in cerebral blood flow (CBF), volume (CBV), and oxygenation (blood-oxygenation
level dependent (BOLD)) during functional activation are important for calculating changes …

Rapid MR imaging of a vascular challenge to focal ischemia in cat brain

AJ De Crespigny, MF Wendland… - Journal of Magnetic …, 1993 - Wiley Online Library
Deoxygenated blood was effectively used as a magnetic resonance (MR) susceptibility
contrast agent to distinguish perfused and nonperfused (ischemic) regions in a focal …