A summary of the biological processes, disease-associated changes, and clinical applications of DNA methylation

GB Andersen, J Tost - DNA Methylation Protocols, 2018 - Springer
DNA methylation at cytosines followed by guanines, CpGs, forms one of the multiple layers
of epigenetic mechanisms controlling and modulating gene expression through chromatin …

DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker

J Tost - DNA methylation: Methods and protocols, 2009 - Springer
DNA methylation occurring on the 5 position of the pyrimidine ring of cytosines in the context
of the dinucleotide sequence CpG forms one of the multiple layers of epigenetic …

[图书][B] DNA methylation protocols

J Tost - 2018 - Springer
It is my great pleasure to introduce the third edition of DNA Methylation: Methods and
Protocols to the scientific and medical community. DNA methylation at cytosines forms one …

DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker

J Tost - Molecular biotechnology, 2010 - Springer
DNA methylation occurring on the 5 position of the pyrimidine ring of cytosines in the context
of the dinucleotide sequence CpG forms one of the multiple layers of epigenetic …

[HTML][HTML] DNA methylation: a timeline of methods and applications

A Harrison, A Parle-McDermott - Frontiers in genetics, 2011 - frontiersin.org
DNA methylation is a biochemical process where a DNA base, usually cytosine, is
enzymatically methylated at the 5-carbon position. An epigenetic modification associated …

[PDF][PDF] New insights on the role of DNA methylation from a global view

K Meier, F Recillas-Targa - Front Biosci (Landmark Ed), 2017 - article.imrpress.com
In mammals, DNA methylation is a crucial epigenetic modification with key functions during
development. Cellular processes that are regulated by DNA methylation comprise X …

Genome‐wide DNA methylation profiling

M Bibikova, JB Fan - Wiley Interdisciplinary Reviews: Systems …, 2010 - Wiley Online Library
DNA methylation plays a critical role in the regulation of gene expression. The ability to
access the methylation status for a large number of genes or the entire genome should …

[HTML][HTML] How to translate DNA methylation biomarkers into clinical practice

W Wagner - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Recent advances in sequencing technologies provide unprecedented opportunities for
epigenetic biomarker development. Particularly the DNA methylation pattern—which is …

Quantitative assessment of DNA methylation: potential applications for disease diagnosis, classification, and prognosis in clinical settings

RM Brena, THM Huang, C Plass - Journal of molecular medicine, 2006 - Springer
Deregulation of the epigenome is now recognized as a major mechanism involved in the
development and progression of human diseases such as cancer. As opposed to the …

DNA methylation methods: Global DNA methylation and methylomic analyses

S Li, TO Tollefsbol - Methods, 2021 - Elsevier
DNA methylation provides a pivotal layer of epigenetic regulation in eukaryotes that has
significant involvement for numerous biological processes in health and disease. The …