Cytosine DNA methylation is essential for mammalian development but understanding of its
spatiotemporal distribution in the developing embryo remains limited,. Here, as part of the …

DNA methylation is a major epigenetic regulatory mechanism for gene expression and cell
differentiation. Until recently, it was still unclear how unmethylated regions in mammalian …

DNA methylation undergoes drastic fluctuation during early mammalian embryogenesis.
The dynamics of global DNA methylation in bovine embryos, however, have mostly been …

DNA methylation is one of the most important heritable epigenetic modifications of the
genome and is involved in the regulation of many cellular processes. Aberrant DNA …

Remodelling the methylome is a hallmark of mammalian development and cell
differentiation. However, current knowledge of DNA methylation dynamics in human tissue …

DNA methylation is involved in a number of important processes such as maintaining
genome stability, silencing of retrotransposons, co-ordinating mono-alleleic expression of …

DNA methylation is a broadly studied epigenetic modification that is essential for normal
mammalian development. Over the years, numerous methodologies were developed trying …

In early embryos, DNA methylation is remodelled to initiate the developmental program but
for mostly unknown reasons, methylation marks are acquired unequally between embryonic …

DNA methylation is an essential epigenetic modification for mammalian development and is
crucial for the establishment and maintenance of cellular identity. Traditionally, DNA …

DNA methylation, a well-known epigenetic modification in mammalian genomes, is
important for development and health. Dysregulation of DNA methylation can cause …