COHCAP: an integrative genomic pipeline for single-nucleotide resolution DNA methylation analysis

CD Warden, H Lee, JD Tompkins, X Li… - Nucleic acids …, 2013 - academic.oup.com
Abstract COHCAP (City of Hope CpG Island Analysis Pipeline) is an algorithm to analyze
single-nucleotide resolution DNA methylation data produced by either an Illumina …

Strategies for discovery and validation of methylated and hydroxymethylated DNA biomarkers

E Olkhov‐Mitsel, B Bapat - Cancer medicine, 2012 - Wiley Online Library
DNA methylation, consisting of the addition of a methyl group at the fifth‐position of cytosine
in a CpG dinucleotide, is one of the most well‐studied epigenetic mechanisms in mammals …

Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates

J Lewin, AO Schmitt, P Adorján, T Hildmann… - …, 2004 - academic.oup.com
Motivation: Methylation of cytosines in DNA plays an important role in the regulation of gene
expression, and the analysis of methylation patterns is fundamental for the understanding of …

[HTML][HTML] Rapid quantification of DNA methylation by measuring relative peak heights in direct bisulfite-PCR sequencing traces

M Jiang, Y Zhang, J Fei, X Chang, W Fan, X Qian… - Laboratory …, 2010 - Elsevier
Various technologies are currently available to quantify DNA methylation. However, rapid
and simple methods for determining the DNA methylation status of CpG sites in genes still …

DNA methylation analysis: choosing the right method

S Kurdyukov, M Bullock - Biology, 2016 - mdpi.com
In the burgeoning field of epigenetics, there are several methods available to determine the
methylation status of DNA samples. However, choosing the method that is best suited to …

[PDF][PDF] Mapping the methylome

EV Epigenomics - Cell Cycle, 2006 - researchgate.net
ABSTRACT DNA methylation is integral to normal development and disease processes.
However, the genomic distribution of methylated sequences—the methylome—is poorly …