High caloric intake during early postnatal development can have long term consequences
for the offspring. We previously reported that the adult offspring of dams fed a high-fat diet …

Rationale Early environment can shape the development and function of the
mesocorticolimbic dopamine (DA) system and represents a possible risk factor for adult …

Objective To utilize a nonhuman primate model to examine the impact of maternal high‐fat
diet (HFD) consumption and pre‐pregnancy obesity on offspring intake of palatable food …

The maternal perinatal environment modulates brain formation, and altered maternal
nutrition has been linked to the development of metabolic and psychiatric disorders in the …

Perturbations in the perinatal environment have been shown to significantly alter mesolimbic
dopamine (DA) and hypothalamic–pituitary–adrenal (HPA) responses to stressors in …

Individuals exposed to high-fat, high-sugar diets before birth have an increased risk of
obesity in later life. Recent studies have shown that these offspring exhibit increased …

Maternal obesity during pregnancy increases the risk of obesity in the offspring. Obesity,
arising from an imbalance of energy intake and expenditure, can be driven by the ingestion …

Consumption of a high-fat diet has been linked to obesity, dyslipidemia and cardiovascular
disease. Less well appreciated are adverse effects on the brain and behavior. Recent …

Increasing evidence suggest that consumption of high-fat diet (HFD) can impact the
maturation of brain circuits, such as during adolescence, which could account for behavioral …

Overweight and obesity in the United States continues to grow at epidemic rates in large part
due to the overconsumption of calorically-dense palatable foods. Identification of factors …