Changes in DNA methylation patterns in subjects exposed to low-dose benzene
Aberrant DNA methylation patterns, including global hypomethylation, gene-specific
hypermethylation/hypomethylation, and loss of imprinting (LOI), are common in acute …
hypermethylation/hypomethylation, and loss of imprinting (LOI), are common in acute …
Is there a link between genome-wide hypomethylation in blood and cancer risk?
K Brennan, JM Flanagan - Cancer prevention research, 2012 - AACR
Cancer cells display widespread genetic and epigenetic abnormalities, but the contribution
to disease risk, particularly in normal tissue before disease, is not yet established. Genome …
to disease risk, particularly in normal tissue before disease, is not yet established. Genome …
Genomic DNA methylation among women in a multiethnic New York City birth cohort
MB Terry, JS Ferris, R Pilsner, JD Flom… - … Biomarkers & Prevention, 2008 - AACR
One plausible mechanism for the environment to alter cancer susceptibility is through DNA
methylation. Alterations in DNA methylation can lead to genomic instability and altered gene …
methylation. Alterations in DNA methylation can lead to genomic instability and altered gene …
DNA methylation changes measured in pre‐diagnostic peripheral blood samples are associated with smoking and lung cancer risk
DNA methylation changes are associated with cigarette smoking. We used the Illumina
Infinium HumanMethylation450 array to determine whether methylation in DNA from pre …
Infinium HumanMethylation450 array to determine whether methylation in DNA from pre …
[HTML][HTML] Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence
A Ruiz-Hernandez, CC Kuo, P Rentero-Garrido… - Clinical …, 2015 - Springer
Current evidence supports the notion that environmental exposures are associated with
DNA-methylation and expression changes that can impact human health. Our objective was …
DNA-methylation and expression changes that can impact human health. Our objective was …
[HTML][HTML] Gene-specific DNA methylation profiles and LINE-1 hypomethylation are associated with myocardial infarction risk
S Guarrera, G Fiorito, NC Onland-Moret, A Russo… - Clinical …, 2015 - Springer
Background DNA methylation profiles are responsive to environmental stimuli and metabolic
shifts. This makes DNA methylation a potential biomarker of environmental-related and …
shifts. This makes DNA methylation a potential biomarker of environmental-related and …
DNA methylation of tumor suppressor genes in clinical remission predicts the relapse risk in acute myeloid leukemia
S Agrawal, M Unterberg, S Koschmieder, U zur Stadt… - Cancer research, 2007 - AACR
Epigenetic changes play an important role in leukemia pathogenesis. DNA methylation is
among the most common alterations in leukemia. The potential role of DNA methylation as a …
among the most common alterations in leukemia. The potential role of DNA methylation as a …
Conserved DNA methylation patterns in healthy blood cells and extensive changes in leukemia measured by a new quantitative technique
Genome wide analysis of DNA methylation provides important information in a variety of
diseases, including cancer. Here, we describe a simple method, Digital Restriction Enzyme …
diseases, including cancer. Here, we describe a simple method, Digital Restriction Enzyme …
[HTML][HTML] DNA methylation in peripheral blood measured by LUMA is associated with breast cancer in a population-based study
X Xu, MD Gammon, H Hernandez-Vargas… - The FASEB …, 2012 - ncbi.nlm.nih.gov
Our purpose was to identify epigenetic markers of breast cancer risk, which can be reliably
measured in peripheral blood and are amenable for large population screening. We used 2 …
measured in peripheral blood and are amenable for large population screening. We used 2 …
DNA methylation in white blood cells: association with risk factors in epidemiologic studies
Alterations in DNA methylation patterns, both at specific loci and overall in the genome, have
been associated with many different health outcomes. In cancer and other diseases, most of …
been associated with many different health outcomes. In cancer and other diseases, most of …