Changes in DNA methylation patterns in subjects exposed to low-dose benzene

V Bollati, A Baccarelli, L Hou, M Bonzini, S Fustinoni… - Cancer research, 2007 - AACR
Aberrant DNA methylation patterns, including global hypomethylation, gene-specific
hypermethylation/hypomethylation, and loss of imprinting (LOI), are common in acute …

Is there a link between genome-wide hypomethylation in blood and cancer risk?

K Brennan, JM Flanagan - Cancer prevention research, 2012 - AACR
Cancer cells display widespread genetic and epigenetic abnormalities, but the contribution
to disease risk, particularly in normal tissue before disease, is not yet established. Genome …

Genomic DNA methylation among women in a multiethnic New York City birth cohort

MB Terry, JS Ferris, R Pilsner, JD Flom… - … Biomarkers & Prevention, 2008 - AACR
One plausible mechanism for the environment to alter cancer susceptibility is through DNA
methylation. Alterations in DNA methylation can lead to genomic instability and altered gene …

DNA methylation changes measured in pre‐diagnostic peripheral blood samples are associated with smoking and lung cancer risk

L Baglietto, E Ponzi, P Haycock… - … journal of cancer, 2017 - Wiley Online Library
DNA methylation changes are associated with cigarette smoking. We used the Illumina
Infinium HumanMethylation450 array to determine whether methylation in DNA from pre …

[HTML][HTML] Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence

A Ruiz-Hernandez, CC Kuo, P Rentero-Garrido… - Clinical …, 2015 - Springer
Current evidence supports the notion that environmental exposures are associated with
DNA-methylation and expression changes that can impact human health. Our objective was …

[HTML][HTML] Gene-specific DNA methylation profiles and LINE-1 hypomethylation are associated with myocardial infarction risk

S Guarrera, G Fiorito, NC Onland-Moret, A Russo… - Clinical …, 2015 - Springer
Background DNA methylation profiles are responsive to environmental stimuli and metabolic
shifts. This makes DNA methylation a potential biomarker of environmental-related and …

DNA methylation of tumor suppressor genes in clinical remission predicts the relapse risk in acute myeloid leukemia

S Agrawal, M Unterberg, S Koschmieder, U zur Stadt… - Cancer research, 2007 - AACR
Epigenetic changes play an important role in leukemia pathogenesis. DNA methylation is
among the most common alterations in leukemia. The potential role of DNA methylation as a …

Conserved DNA methylation patterns in healthy blood cells and extensive changes in leukemia measured by a new quantitative technique

J Jelinek, S Liang, Y Lu, R He, LS Ramagli, EJ Shpall… - Epigenetics, 2012 - Taylor & Francis
Genome wide analysis of DNA methylation provides important information in a variety of
diseases, including cancer. Here, we describe a simple method, Digital Restriction Enzyme …

[HTML][HTML] DNA methylation in peripheral blood measured by LUMA is associated with breast cancer in a population-based study

X Xu, MD Gammon, H Hernandez-Vargas… - The FASEB …, 2012 - ncbi.nlm.nih.gov
Our purpose was to identify epigenetic markers of breast cancer risk, which can be reliably
measured in peripheral blood and are amenable for large population screening. We used 2 …

DNA methylation in white blood cells: association with risk factors in epidemiologic studies

MB Terry, L Delgado-Cruzata, N Vin-Raviv, HC Wu… - Epigenetics, 2011 - Taylor & Francis
Alterations in DNA methylation patterns, both at specific loci and overall in the genome, have
been associated with many different health outcomes. In cancer and other diseases, most of …