8: 8 Perfluoroalkyl phosphinic acid affects neurobehavioral development, thyroid disruption, and DNA methylation in developing zebrafish

S Kim, KM Stroski, G Killeen, C Smitherman… - Science of the Total …, 2020 - Elsevier
Recent studies have reported potential neurotoxicity and epigenetic alteration associated
with exposure to several per-and polyfluoroalkyl substances (PFASs). However, such …

Embryonic exposure to PFAS causes long-term, compound-specific behavioral alterations in zebrafish

AB Hawkey, M Mead, S Natarajan, A Gondal… - Neurotoxicology and …, 2023 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) are commonly used as surfactants and coatings
for industrial processes and consumer products. These compounds have been increasingly …

Developmental Neurotoxicity of Perfluorinated Chemicals Modeled in Vitro

TA Slotkin, EA MacKillop, RL Melnick… - Environmental …, 2008 - ehp.niehs.nih.gov
Background The widespread detection of perfluoroalkyl acids and their derivatives in wildlife
and humans, and their entry into the immature brain, raise increasing concern about …

[HTML][HTML] Assessment of unique behavioral, morphological, and molecular alterations in the comparative developmental toxicity profiles of PFOA, PFHxA, and PFBA …

O Wasel, KM Thompson, JL Freeman - Environment international, 2022 - Elsevier
Perfluoroalkyl substances (PFAS) are a class of synthetic chemicals that are persistent in the
environment. Due to adverse health outcomes associated with longer chain PFAS, shorter …

Significant variability in the developmental toxicity of representative perfluoroalkyl acids as a function of chemical speciation

Y Bai, Q Wang, J Li, B Zhou, PKS Lam… - … science & technology, 2023 - ACS Publications
Current toxicological data of perfluoroalkyl acids (PFAAs) are disparate under similar
exposure scenarios. To find the cause of the conflicting data, this study examined the …

Thyroid endocrine disruption effects of perfluoroalkyl phosphinic acids on zebrafish at early development

M Liu, S Yi, P Chen, M Chen, W Zhong, J Yang… - Science of the total …, 2019 - Elsevier
Perfluoroalkyl phosphinic acids (PFPiAs, including 6: 6, 6: 8 and 8: 8 PFPiAs) are one kind of
emerging perfluoroalkyl substances and usually used as leveling and wetting agents in …

Sulfonamide functional head on short-chain perfluorinated substance drives developmental toxicity

Y Rericha, D Cao, L Truong, MT Simonich, JA Field… - Iscience, 2022 - cell.com
Per-and polyfluoroalkyl substances (PFAS) are ubiquitously detected in environmental and
biological samples and cause adverse health effects. Studies have predominately focused …

Subtle morphometric, behavioral and gene expression effects in larval zebrafish exposed to PFHxA, PFHxS and 6: 2 FTOH

KM Annunziato, CE Jantzen, MC Gronske, KR Cooper - Aquatic toxicology, 2019 - Elsevier
Recent studies of perfluoroalkylated substances (PFASs) have focused on the toxicity of
long chain PFASs, such as PFOS or PFOA, which have been demonstrated to cause an …

Developmental and mitochondrial toxicity assessment of perfluoroheptanoic acid (PFHpA) in zebrafish (Danio rerio)

M Huang, E Ivantsova, I Konig, N Patel… - Environmental …, 2023 - Elsevier
The potential toxicity of several perfluoroalkyl and polyfluoroalkyl substances (PFASs) to
aquatic species are not well understood. Here, we assessed the sub-lethal toxicity potential …

Evaluation of developmental toxicity, developmental neurotoxicity, and tissue dose in zebrafish exposed to GenX and other PFAS

S Gaballah, A Swank, JR Sobus… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: Per-and polyfluoroalkyl substances (PFAS) are a diverse class of industrial
chemicals with widespread environmental occurrence. Exposure to long-chain PFAS is …