[HTML][HTML] The influence of early environment and micronutrient availability on developmental epigenetic programming: lessons from the placenta
R Sainty, MJ Silver, AM Prentice… - Frontiers in Cell and …, 2023 - frontiersin.org
DNA methylation is the most commonly studied epigenetic mark in humans, as it is well
recognised as a stable, heritable mark that can affect genome function and influence gene …
recognised as a stable, heritable mark that can affect genome function and influence gene …
Locus-specific DNA methylation reprogramming during early porcine embryogenesis
During early mammalian embryogenesis, there is a wave of DNA demethylation
postfertilization and de novo methylation around implantation. The paternal genome …
postfertilization and de novo methylation around implantation. The paternal genome …
[HTML][HTML] Maternal genome-wide DNA methylation patterns and congenital heart defects
S Chowdhury, SW Erickson, SL MacLeod, MA Cleves… - PloS one, 2011 - journals.plos.org
The majority of congenital heart defects (CHDs) are thought to result from the interaction
between multiple genetic, epigenetic, environmental, and lifestyle factors. Epigenetic …
between multiple genetic, epigenetic, environmental, and lifestyle factors. Epigenetic …
Cell specific patterns of methylation in the human placenta
A Grigoriu, JC Ferreira, S Choufani, D Baczyk… - Epigenetics, 2011 - Taylor & Francis
Epigenetic processes, such as DNA methylation, are known to regulate tissue specific gene
expression. We explored this concept in the placenta to define whether DNA methylation is …
expression. We explored this concept in the placenta to define whether DNA methylation is …
The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes
Integrating the genotype with epigenetic marks holds the promise of better understanding
the biology that underlies the complex interactions of inherited and environmental …
the biology that underlies the complex interactions of inherited and environmental …
[HTML][HTML] DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus
Background DNA methylation is of pivotal importance during development. Previous
genome-wide studies identified numerous differentially methylated regions upon …
genome-wide studies identified numerous differentially methylated regions upon …
[HTML][HTML] Analysis of epigenetic changes in survivors of preterm birth reveals the effect of gestational age and evidence for a long term legacy
MN Cruickshank, A Oshlack, C Theda, PG Davis… - Genome medicine, 2013 - Springer
Background Preterm birth confers a high risk of adverse long term health outcomes for
survivors, yet the underlying molecular mechanisms are unclear. We hypothesized that …
survivors, yet the underlying molecular mechanisms are unclear. We hypothesized that …
[HTML][HTML] DNA-methylation profiling of fetal tissues reveals marked epigenetic differences between chorionic and amniotic samples
C Eckmann-Scholz, S Bens, J Kolarova… - Plos one, 2012 - journals.plos.org
Epigenetic mechanisms including DNA methylation are supposed to play a key role in fetal
development. Here we have investigated fetal DNA-methylation levels of 27,578 CpG loci in …
development. Here we have investigated fetal DNA-methylation levels of 27,578 CpG loci in …
[HTML][HTML] DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse
We have developed a mouse DNA methylation array that contains 296,070 probes
representing the diversity of mouse DNA methylation biology. We present a mouse …
representing the diversity of mouse DNA methylation biology. We present a mouse …
Adaptation of the targeted capture Methyl-Seq platform for the mouse genome identifies novel tissue-specific DNA methylation patterns of genes involved in …
Methyl-Seq was recently developed as a targeted approach to assess DNA methylation
(DNAm) at a genome-wide level in human. We adapted it for mouse and sought to examine …
(DNAm) at a genome-wide level in human. We adapted it for mouse and sought to examine …