Dear Prof. Gendelman: Melatonin MLT) or N-acetyl-5-methoxy-tryptamine is an indoleamine
synthesized and immediately secreted in the blood during the night darkness hours by the …

The pathogenesis of a COVID-19 respiratory infection, in a major way, is related to what is
referred to as the cytokine storm [cytokine storm syndrome (CSS, hypercytokinemia, etc.], ie …

As the COVID‐19 pandemic grows, several therapeutic candidates are being tested or
undergoing clinical trials. Although prophylactic vaccination against SARS‐CoV‐2 infection …

Objectives This study aimed to determine the effect of melatonin on thrombosis, sepsis, and
mortality rate in adult patients with severe coronavirus infection (COVID-19). Methods This …

No effective antiviral drugs and vaccines are available for the treatment of patients with
severe coronavirus 2019 (COVID-19). Therefore, available, safe, and inexpensive drugs and …

This review paper highlights the role of melatonin in many diseases, coronavirus (SARS-
CoV-2) disease (covid-19) and multi-physiological functions in plants. Based on its …

Competition among pharmaceutical companies to develop safe and effective vaccines
against SARS-CoV-2 is high. However, based on the prior experience with the influenza …

The rapid escalation of pandemic health threats associated with the novel, pathogenic
SARS-CoV-2 coronavirus poses unprecedented challenges as proven effective vaccines …

Melatonin is a versatile molecule, synthesized not only by the pineal gland, but also in small
amounts by many other organs like retina, gastrointestinal tract, thymus, bone marrow …

COVID-19 is associated with oxidative stress, peripheral hyper inflammation, and
neuroinflammation, especially in individuals with a more severe form of the disease. Some …