Genome-wide 5-hydroxymethylome analysis of a rodent hepatocarcinogen model reveals
that 5-hydroxymethylcytosine-dependent active DNA demethylation may be functionally …

Candidate gene-based studies have identified a handful of aberrant CpG DNA methylation
events in prostate cancer. However, DNA methylation profiles have not been compared on a …

Abstract MethBank (http://bigd. big. ac. cn/methbank) is a database that integrates high-
quality DNA methylomes across a variety of species and provides an interactive browser for …

DNA methylation is a tightly regulated epigenetic mark associated with transcriptional
repression. Next-generation sequencing of purified methylated DNA obtained from early …

Alterations of DNA methylation, which result in chromosomal instability and silencing of
tumor‐related genes, are among the most consistent epigenetic changes observed in …

Cytosine methylation is the most common covalent modification of DNA in eukaryotes. DNA
methylation has an important role in many aspects of biology, including development and …

DNA methylation is an epigenetic modification that plays a key role in gene regulation.
Previous studies have investigated its genetic basis by mapping genetic variants that are …

DNA methylation is an important epigenetic modification for genomic regulation in higher
organisms that plays a crucial role in the initiation and progression of diseases. The …

DNA methylation is an important epigenetic modification involved in many biological
processes and diseases. Many studies have mapped DNA methylation changes associated …

DNA methylation is an important component of the epigenetic control of genome functions.
Understanding the regulation of the DNA Methyltransferase (dnmt1) gene expression is …