DNA methylation contributes to natural human variation
DNA methylation patterns are important for establishing cell, tissue, and organism
phenotypes, but little is known about their contribution to natural human variation. To …
phenotypes, but little is known about their contribution to natural human variation. To …
High-resolution mapping of DNA methylation in human genome using oligonucleotide tiling array
H Hayashi, G Nagae, S Tsutsumi, K Kaneshiro… - Human genetics, 2007 - Springer
DNA methylation is an epigenetic mark crucial in regulation of gene expression. Aberrant
DNA methylation causes silencing of tumor suppressor genes and promotes chromosomal …
DNA methylation causes silencing of tumor suppressor genes and promotes chromosomal …
Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets
JM Ordway, JA Bedell, RW Citek, A Nunberg… - …, 2006 - academic.oup.com
Using a unique microarray platform for cytosine methylation profiling, the DNA methylation
landscape of the human genome was monitored at more than 21 000 sites, including 79% of …
landscape of the human genome was monitored at more than 21 000 sites, including 79% of …
DNA methylation profiling of human chromosomes 6, 20 and 22
F Eckhardt, J Lewin, R Cortese, VK Rakyan, J Attwood… - Nature …, 2006 - nature.com
DNA methylation is the most stable type of epigenetic modification modulating the
transcriptional plasticity of mammalian genomes. Using bisulfite DNA sequencing, we report …
transcriptional plasticity of mammalian genomes. Using bisulfite DNA sequencing, we report …
Methylated DNA immunoprecipitation (medip)
F Mohn, M Weber, D Schübeler, TC Roloff - DNA methylation: methods …, 2009 - Springer
Methylated DNA immunoprecipitation (MeDIP) is a versatile immunocapturing approach for
unbiased detection of methylated DNA. In brief, genomic DNA is randomly sheared by …
unbiased detection of methylated DNA. In brief, genomic DNA is randomly sheared by …
Genome-wide DNA methylation analysis of archival formalin-fixed paraffin-embedded tissue using the Illumina Infinium HumanMethylation27 BeadChip
C Thirlwell, M Eymard, A Feber, A Teschendorff… - Methods, 2010 - Elsevier
Aberrant DNA methylation of promoter and other genomic regions can lead to changes in
gene expression, such as over-expression of oncogenes and the silencing of tumour …
gene expression, such as over-expression of oncogenes and the silencing of tumour …
MBD-isolated Genome Sequencing provides a high-throughput and comprehensive survey of DNA methylation in the human genome
DNA methylation is an epigenetic modification involved in both normal developmental
processes and disease states through the modulation of gene expression and the …
processes and disease states through the modulation of gene expression and the …
Validation of a DNA methylation microarray for 285,000 CpG sites in the mouse genome
Mouse has been extensively used as a model organism in many studies to characterize
biological pathways and drug effects and to mimic human diseases. Similar DNA sequences …
biological pathways and drug effects and to mimic human diseases. Similar DNA sequences …
Genome-wide quantitative assessment of variation in DNA methylation patterns
H Xie, M Wang, A De Andrade, MF Bonaldo… - Nucleic acids …, 2011 - academic.oup.com
Genomic DNA methylation contributes substantively to transcriptional regulations that
underlie mammalian development and cellular differentiation. Much effort has been made to …
underlie mammalian development and cellular differentiation. Much effort has been made to …
Identification of preferential target sites for human DNA methyltransferases
SH Choi, K Heo, HM Byun, W An, W Lu… - Nucleic acids …, 2011 - academic.oup.com
DNA methyltransferases (DNMTs) play an important role in establishing and maintaining
DNA methylation. Aberrant expression of DNMTs and their isoforms has been found in many …
DNA methylation. Aberrant expression of DNMTs and their isoforms has been found in many …