Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates

C Gurnot, I Martin-Subero, SM Mah, W Weikum… - Epigenetics, 2015 - Taylor & Francis
Some but not all neonates are affected by prenatal exposure to serotonin reuptake inhibitor
antidepressants (SRI) and maternal mood disturbances. Distinguishing the impact of these 2 …

Prenatal maternal antidepressants, anxiety, and depression and offspring DNA methylation: epigenome-wide associations at birth and persistence into early …

A Cardenas, S Faleschini, A Cortes Hidalgo… - Clinical …, 2019 - Springer
Background Maternal mood disorders and their treatment during pregnancy may have
effects on the offspring epigenome. We aim to evaluate associations of maternal prenatal …

Genome-wide DNA methylation in neonates exposed to maternal depression, anxiety, or SSRI medication during pregnancy

AL Non, AM Binder, LD Kubzansky, KB Michels - Epigenetics, 2014 - Taylor & Francis
Despite the high prevalence of depression, anxiety, and use of antidepressant medications
during pregnancy, there is much uncertainty around the impact of high levels of distress or …

DNA methylation in neonates born to women receiving psychiatric care

JW Schroeder, AK Smith, PA Brennan, KN Conneely… - Epigenetics, 2012 - Taylor & Francis
Prenatal exposure both to maternal psychiatric illness and psychiatric medication has been
linked with adverse child outcomes that affect physiological, emotional and psychiatric …

Effects of prenatal exposure to (es) citalopram and maternal depression during pregnancy on DNA methylation and child neurodevelopment

EW Olstad, HME Nordeng, GK Sandve, R Lyle… - Translational …, 2023 - nature.com
Studies assessing associations between prenatal exposure to antidepressants, maternal
depression, and offspring DNA methylation (DNAm) have been inconsistent. Here, we …

DNA methylation signatures in human neonatal blood following maternal antenatal corticosteroid treatment

B Kim, A Sasaki, K Murphy, SG Matthews - Translational Psychiatry, 2022 - nature.com
Antenatal corticosteroids (ACS) are used to treat women at risk of preterm birth to improve
neonatal survival. Though affected children may be at long-term risk of neurobehavioural …

Profiling placental DNA methylation associated with maternal SSRI treatment during pregnancy

AM Inkster, C Konwar, MS Peñaherrera, U Brain… - Scientific Reports, 2022 - nature.com
Selective serotonin reuptake inhibitors (SSRIs) for treatment of prenatal maternal depression
have been associated with neonatal neurobehavioral disturbances, though the molecular …

Perinatal exposure to the SSRI paroxetine alters the methylome landscape of the developing dentate gyrus

ME Glover, CR McCoy, EA Shupe… - European Journal of …, 2019 - Wiley Online Library
Evidence in humans and rodents suggests that perinatal exposure to selective serotonin
reuptake inhibitor (SSRI) antidepressants can have serious long‐term consequences in …

Prenatal medication exposure and epigenetic outcomes: a systematic literature review and recommendations for prenatal pharmacoepigenetic studies

EW Olstad, HME Nordeng, K Gervin - Epigenetics, 2022 - Taylor & Francis
When used during pregnancy, analgesics and psychotropics pass the placenta to enter the
foetal circulation and may induce epigenetic modifications. Where such modifications occur …

Neonatal outcomes after prenatal exposure to selective serotonin reuptake inhibitor antidepressants and maternal depression using population-based linked health …

TF Oberlander, W Warburton, S Misri… - Archives of general …, 2006 - jamanetwork.com
Context Prenatal exposure to selective serotonin reuptake inhibitor (SSRI) antidepressants
and maternal depression both alter neonatal health, and distinguishing the effects of each …