Chronic diseases account for over 60% of all deaths worldwide according to the World
Health Organization reports. Majority of cases are triggered by environmental exposures that …

Diet plays an important role in the development and prevention of cardiovascular disease
(CVD), but the molecular mechanisms are not fully understood. DNA methylation has been …

DNA methylation is a key component of the epigenetic machinery that is responsible for
regulating gene expression and, therefore, cell function. Patterns of DNA methylation …

In living systems, the mechanisms of inheritance involving gene expression are operated by
(i) the traditional model of genetics where the deoxyribonucleic acid (DNA) transcription and …

Cancer can take many years to develop from initiation to progression. The long period of
development might represent an opportunity to use multi-functional, multi-targeted …

Over the past decades, DNA methylation has been proposed as a molecular mechanism
underlying the positive or negative effects of diet on human health. Despite the number of …

Background Oxidative stress has been related to type 2 diabetes (T2D) and cardiovascular
disease (CVD), the leading global cause of death. Contributions of environmental factors …

Nutritional epigenetics has emerged as a novel mechanism underlying gene–diet
interactions, further elucidating the modulatory role of nutrition in aging and age-related …

Aging is a major risk factor for individuals' health problems. Moreover, environmental signals
have a widespread influence on the aging process. Epigenetic modification, eg DNA …

Methylation is a reversible modification of DNA participating in epigenetic regulation of gene
expression. It is now clear that atherosclerosis is associated with aberrant DNA methylation …