A distinctive DNA methylation pattern in insufficient sleep
A Lahtinen, S Puttonen, P Vanttola, K Viitasalo… - Scientific reports, 2019 - nature.com
Short sleep duration or insomnia may lead to an increased risk of various psychiatric and
cardio-metabolic conditions. Since DNA methylation plays a critical role in the regulation of …
cardio-metabolic conditions. Since DNA methylation plays a critical role in the regulation of …
Epigenomics of total acute sleep deprivation in relation to genome-wide DNA methylation profiles and RNA expression
EK Nilsson, AE Boström, J Mwinyi… - Omics: a journal of …, 2016 - liebertpub.com
Despite an established link between sleep deprivation and epigenetic processes in humans,
it remains unclear to what extent sleep deprivation modulates DNA methylation. We …
it remains unclear to what extent sleep deprivation modulates DNA methylation. We …
Genome‐wide DNA methylation patterns associated with sleep and mental health in children: a population‐based study
ME Koopman‐Verhoeff, RH Mulder… - Journal of Child …, 2020 - Wiley Online Library
Background DNA methylation (DNAm) has been implicated in the biology of sleep. Yet, how
DNAm patterns across the genome relate to different sleep outcomes, and whether these …
DNAm patterns across the genome relate to different sleep outcomes, and whether these …
Whole Genome DNA Methylation Analysis of Obstructive Sleep Apnea: IL1R2,NPR2, AR, SP140 Methylation and Clinical Phenotype
Abstract Study Objectives We hypothesized that DNA methylation patterns may contribute to
disease severity or the development of hypertension and excessive daytime sleepiness …
disease severity or the development of hypertension and excessive daytime sleepiness …
Epigenome-wide association analysis of daytime sleepiness in the Multi-Ethnic Study of Atherosclerosis reveals African-American-specific associations
Abstract Study Objectives Daytime sleepiness is a consequence of inadequate sleep, sleep–
wake control disorder, or other medical conditions. Population variability in prevalence of …
wake control disorder, or other medical conditions. Population variability in prevalence of …
Combining Human Epigenetics and Sleep Studies in Caenorhabditis elegans: A Cross-Species Approach for Finding Conserved Genes Regulating Sleep
Abstract Study Objectives: We aimed to test a combined approach to identify conserved
genes regulating sleep and to explore the association between DNA methylation and sleep …
genes regulating sleep and to explore the association between DNA methylation and sleep …
Epigenetic dysregulation of genes related to synaptic long-term depression among adolescents with depressive disorder and sleep symptoms
AJ Ämmälä, AS Urrila, A Lahtinen, O Santangeli… - Sleep medicine, 2019 - Elsevier
Objectives This study aimed to test the hypothesis that sleep and depression have
independent effects on brain development and plasticity in adolescents, and that these …
independent effects on brain development and plasticity in adolescents, and that these …
Longitudinal associations of DNA methylation and sleep in children: a meta-analysis
S Sammallahti, ME Koopman-Verhoeff, AC Binter… - Clinical …, 2022 - Springer
Background Sleep is important for healthy functioning in children. Numerous genetic and
environmental factors, from conception onwards, may influence this phenotype. Epigenetic …
environmental factors, from conception onwards, may influence this phenotype. Epigenetic …
The genome-wide landscape of DNA methylation and hydroxymethylation in response to sleep deprivation impacts on synaptic plasticity genes
R Massart, M Freyburger, M Suderman… - Translational …, 2014 - nature.com
Sleep is critical for normal brain function and mental health. However, the molecular
mechanisms mediating the impact of sleep loss on both cognition and the sleep …
mechanisms mediating the impact of sleep loss on both cognition and the sleep …
Sleep deprivation and the epigenome
Sleep deprivation disrupts the lives of millions of people every day and has a profound
impact on the molecular biology of the brain. These effects begin as changes within a …
impact on the molecular biology of the brain. These effects begin as changes within a …
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