Mechanisms of DNA methylation, methyl-CpG recognition, and demethylation in mammals
X Cheng, H Hashimoto, JR Horton, X Zhang - Handbook of epigenetics, 2011 - Elsevier
Publisher Summary This chapter summarizes the recent structural and biochemical
advances in the study of mammalian DNA MTases and their associated protein factor (s) …
advances in the study of mammalian DNA MTases and their associated protein factor (s) …
[PDF][PDF] The role of mammalian DNA methyltransferases in the regulation of gene expression
J Turek-Plewa, PP Jagodzinski - Cellular and Molecular Biology Letters, 2005 - Citeseer
The term epigenetic modification denotes reversible traits of gene expression that do not
include alterations to the DNA sequence. These epigenetic alterations are responsible for …
include alterations to the DNA sequence. These epigenetic alterations are responsible for …
Mammalian DNA methyltransferases: a structural perspective
X Cheng, RM Blumenthal - Structure, 2008 - cell.com
The methylation of mammalian DNA, primarily at CpG dinucleotides, has long been
recognized to play a major role in controlling gene expression, among other functions. Given …
recognized to play a major role in controlling gene expression, among other functions. Given …
DNA methylation and reader or writer proteins: Differentiation and disease
M Ehrlich - Chromatin Readers in Health and Disease, 2024 - Elsevier
DNA methylation plays a central role in development serving as a tissue-specific, cell type-
specific, and developmental stage-specific memory mark overlaid on genetics, the sequence …
specific, and developmental stage-specific memory mark overlaid on genetics, the sequence …
DNA methylation‐mediated epigenetic control
A Rottach, H Leonhardt, F Spada - Journal of cellular …, 2009 - Wiley Online Library
During differentiation and development cells undergo dramatic morphological and functional
changes without any change in the DNA sequence. The underlying changes of gene …
changes without any change in the DNA sequence. The underlying changes of gene …
Genomic DNA methylation: the mark and its mediators
Methylation of DNA at position five of the cytosine ring occurs at most CpG dinucleotides in
the mammalian genome and is essential for embryonic viability. With several of the key …
the mammalian genome and is essential for embryonic viability. With several of the key …
Regulation of DNA methyltransferase 1
F Spada, U Rothbauer, K Zolghadr… - Advances in enzyme …, 2006 - Elsevier
Although essentially all cells of a mammalian organism contain the same genetic
information they may differ dramatically in form and function. This cellular differentiation is …
information they may differ dramatically in form and function. This cellular differentiation is …
Molecular processes connecting DNA methylation patterns with DNA methyltransferases and histone modifications in mammalian genomes
A Jeltsch, J Broche, P Bashtrykov - Genes, 2018 - mdpi.com
DNA methylation is an essential part of the epigenome chromatin modification network,
which also comprises several covalent histone protein post-translational modifications. All …
which also comprises several covalent histone protein post-translational modifications. All …
Establishment and maintenance of DNA methylation patterns in mammals
T Chen, E Li - DNA Methylation: Basic Mechanisms, 2006 - Springer
In mammals, CpG methylation patterns are established and maintained during development
by the Dnmt1 and Dnmt3 families of DNA methyltransferases. These enzymes share …
by the Dnmt1 and Dnmt3 families of DNA methyltransferases. These enzymes share …
[HTML][HTML] Mediating and maintaining methylation while minimizing mutation: Recent advances on mammalian DNA methyltransferases
X Cheng, RM Blumenthal - Current opinion in structural biology, 2022 - Elsevier
Mammalian genomes are methylated on carbon-5 of many cytosines, mostly in CpG
dinucleotides. Methylation patterns are maintained during mitosis via DNMT1, and …
dinucleotides. Methylation patterns are maintained during mitosis via DNMT1, and …
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