Atypical hemolytic uremic syndrome: new challenges in the complement blockage era

AI Avila Bernabeu, T Cavero Escribano, M Cao Vilarino - Nephron, 2020 - karger.com
Atypical hemolytic uremic syndrome (aHUS) is a rare cause of thrombotic microangiopathy
(TMA), characterized by microangiopathic hemolytic anemia, consumptive …

[HTML][HTML] Atypical and secondary hemolytic uremic syndromes have a distinct presentation and no common genetic risk factors

A Le Clech, N Simon-Tillaux, F Provôt, Y Delmas… - Kidney international, 2019 - Elsevier
Secondary hemolytic uremic syndrome (HUS) is a heterogeneous group of thrombotic
microangiopathies associated with various underlying conditions. Whether it belongs to the …

[HTML][HTML] Atypical hemolytic uremic syndrome (aHUS): treating the patient

J Laurence - Clin Adv Hematol Oncol, 2013 - hematologyandoncology.net
The 3 major thrombotic microangiopathies (TMAs) are thrombotic thrombocytopenic purpura
(TTP), atypical hemolytic uremic syndrome (aHUS), and Shiga toxin–producing Escherichia …

Atypical hemolytic uremic syndrome: a brief review

K Zhang, Y Lu, KT Harley, MH Tran - Hematology reports, 2017 - mdpi.com
Atypical hemolytic uremic syndrome (aHUS) is a disease characterized by the triad of
microangiopathic hemolytic anemia, thrombocytopenia and acute kidney injury. The …

Clinical practice: today's understanding of the haemolytic uraemic syndrome

J Scheiring, A Rosales, LB Zimmerhackl - European journal of pediatrics, 2010 - Springer
The haemolytic uraemic syndrome (HUS) includes the triad of haemolytic anaemia,
thrombocytopenia, and acute renal failure. The classical form [D (+) HUS] is caused by …

Comprehensive genetic analysis of complement and coagulation genes in atypical hemolytic uremic syndrome

F Bu, T Maga, NC Meyer, K Wang… - Journal of the …, 2014 - journals.lww.com
Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy caused by
uncontrolled activation of the alternative pathway of complement at the cell surface level that …

[HTML][HTML] Hemolytic uremic syndrome

N Canpolat - Turkish Archives of Pediatrics/Türk Pediatri Arşivi, 2015 - ncbi.nlm.nih.gov
Hemolytic uremic syndrome (HUS) is a clinical syndrome characterized by the triad of
thrombotic microangiopathy, thrombocytopenia, and acute kidney injury. Hemolytic uremic …

Atypical hemolytic‐uremic syndrome: an update on pathophysiology, diagnosis, and treatment

R Raina, V Krishnappa, T Blaha, T Kann… - Therapeutic …, 2019 - Wiley Online Library
Atypical hemolytic uremic syndrome (aHUS), a rare variant of thrombotic microangiopathy, is
characterized by microangiopathic hemolytic anemia, thrombocytopenia, and renal …

Insights into hemolytic uremic syndrome: segregation of three independent predisposition factors in a large, multiple affected pedigree

J Esparza-Gordillo, EG de Jorge, CA Garrido… - Molecular …, 2006 - Elsevier
Mutations in the complement regulators factor H, membrane cofactor protein (MCP), and
factor I are associated with atypical hemolytic uremic syndrome (aHUS, MIM 235400) …

Haemolytic uraemic syndrome

M Michael, A Bagga, SE Sartain, RJH Smith - The Lancet, 2022 - thelancet.com
Haemolytic uraemic syndrome (HUS) is a heterogeneous group of diseases that result in a
common pathology, thrombotic microangiopathy, which is classically characterised by the …