Background Growing evidence shows that epigenetic modifications play a role in
Alzheimer's disease (AD). We performed an epigenome-wide association study (EWAS) to …

Epigenome-wide association studies of Alzheimer's disease have highlighted
neuropathology-associated DNA methylation differences, although existing studies have …

Late-onset Alzheimer's disease (AD) is a complex age-related neurodegenerative disorder
that likely involves epigenetic factors. To better understand the epigenetic state associated …

Alzheimer's disease (AD) is the most common cause of dementia with advancing age as its
strongest risk factor. AD neuropathologic change (ADNC) is known to be associated with …

Alzheimer's disease (AD) is characterized by specific alterations of brain DNA methylation
(DNAm) patterns. Age and sex, two major risk factors for AD, are also known to largely affect …

Evidence supports a role for epigenetic mechanisms in the pathogenesis of late-onset
Alzheimer's disease (LOAD), but little has been done on a genome-wide scale to identify …

Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by the
progressive accumulation of amyloid-beta and neurofibrillary tangles of tau in the neocortex …

Background Drawing the epigenome landscape of Alzheimer's disease (AD) still remains a
challenge. To characterize the epigenetic molecular basis of the human hippocampus in AD …

Objective We explore the role of DNA methylation in Alzheimer's disease (AD). To elucidate
where DNA methylation falls along the causal pathway linking risk factors to disease, we …

Research over the years has shown that causes of Alzheimer's disease are not well
understood, but over the past years, the involvement of epigenetic mechanisms in the …