Meffil: efficient normalisation and analysis of very large DNA methylation samples
Background Technological advances in high throughput DNA methylation microarrays have
allowed dramatic growth of a new branch of epigenetic epidemiology. DNA methylation …
allowed dramatic growth of a new branch of epigenetic epidemiology. DNA methylation …
Meffil: efficient normalization and analysis of very large DNA methylation datasets
Motivation DNA methylation datasets are growing ever larger both in sample size and
genome coverage. Novel computational solutions are required to efficiently handle these …
genome coverage. Novel computational solutions are required to efficiently handle these …
[HTML][HTML] GMQN: a reference-based method for correcting batch effects and probe bias in humanmethylation beadchip
The Illumina HumanMethylation BeadChip is one of the most cost-effective methods to
quantify DNA methylation levels at single-base resolution across the human genome, which …
quantify DNA methylation levels at single-base resolution across the human genome, which …
Bigmelon: tools for analysing large DNA methylation datasets
Motivation The datasets generated by DNA methylation analyses are getting bigger. With the
release of the HumanMethylationEPIC micro-array and datasets containing thousands of …
release of the HumanMethylationEPIC micro-array and datasets containing thousands of …
Calling differential DNA methylation at cell-type resolution: an objective status-quo
H Jing, SC Zheng, CE Breeze, S Beck… - BioRxiv, 2019 - biorxiv.org
Due to cost and logistical reasons, Epigenome-Wide-Association Studies (EWAS) are
normally performed in complex tissues, resulting in average DNA methylation profiles over …
normally performed in complex tissues, resulting in average DNA methylation profiles over …
[HTML][HTML] Improved filtering of DNA methylation microarray data by detection p values and its impact on downstream analyses
JA Heiss, AC Just - Clinical epigenetics, 2019 - Springer
Background DNA methylation microarrays are popular for epigenome-wide association
studies (EWAS), but spurious values complicate downstream analysis and threaten …
studies (EWAS), but spurious values complicate downstream analysis and threaten …
GLINT: a user-friendly toolset for the analysis of high-throughput DNA-methylation array data
GLINT is a user-friendly command-line toolset for fast analysis of genome-wide DNA
methylation data generated using the Illumina human methylation arrays. GLINT, which …
methylation data generated using the Illumina human methylation arrays. GLINT, which …
MethParquet: An R Package for Rapid and Efficient DNA Methylation Association Analysis Adopting Apache Parquet
Genome-wide DNA methylation (DNAm) profiling is indispensable for unveiling how DNAm
regulates biological pathways and individual phenotypes. However, managing and …
regulates biological pathways and individual phenotypes. However, managing and …
[HTML][HTML] DMRforPairs: identifying differentially methylated regions between unique samples using array based methylation profiles
MA Rijlaarsdam, YG van der Zwan, LCJ Dorssers… - BMC …, 2014 - Springer
Background Array based methylation profiling is a cost-effective solution to study the
association between genome methylation and human disease & development. Available …
association between genome methylation and human disease & development. Available …
recountmethylation enables flexible analysis of public blood DNA methylation array data
Thousands of DNA methylation (DNAm) array samples from human blood are publicly
available on the Gene Expression Omnibus (GEO), but they remain underutilized for …
available on the Gene Expression Omnibus (GEO), but they remain underutilized for …